Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Khoo Teck Puat-National University Children's Medical Institute, National University Hospital, National University Health System, Singapore.
Pediatr Allergy Immunol. 2018 Feb;29(1):18-27. doi: 10.1111/pai.12820. Epub 2017 Nov 22.
Emerging evidence for the early introduction of allergenic foods for the prevention of food allergies, such as peanut allergy in Western populations, has led to the recent publication of guidelines in the USA and Europe recommending early peanut introduction for high-risk infants with severe eczema or egg allergy. Peanut allergy is, however, much less prevalent in Asia compared to the West. Varying patterns of food allergy are seen even within Asian countries-such as a predominance of wheat allergy in Japan and Thailand and shellfish allergy in Singapore and the Philippines. Customs and traditions, such as diet and infant feeding practices, also differ between Asian populations. Hence, there are unique challenges in adapting guidelines on early allergenic food introduction to the Asian setting. In this paper, we review the evidence and discuss the possible approaches to guide the timely introduction of allergenic food in high-risk infants in Asia.
越来越多的证据表明，早期引入过敏原性食物（如西方人群中的花生过敏）可以预防食物过敏，例如最近在美国和欧洲发布的指南建议，严重湿疹或鸡蛋过敏的高危婴儿应早期引入花生。然而，与西方相比，亚洲的花生过敏要少见得多。即使在亚洲国家内部，食物过敏的模式也存在差异，例如日本和泰国以小麦过敏为主，新加坡和菲律宾则以贝类过敏为主。饮食习惯和婴儿喂养方式等习俗和传统也因亚洲人群而异。因此，在将早期过敏原性食物引入的指南适用于亚洲环境方面存在独特的挑战。在本文中，我们回顾了相关证据，并讨论了指导亚洲高危婴儿适时引入过敏原性食物的可能方法。
