Priority Research Centre for Healthy Lungs, University of Newcastle, Newcastle, NSW
Priority Research Centre for Healthy Lungs, University of Newcastle, Newcastle, NSW.
Med J Aust. 2018 Jul 16;209(S2):S28-S33. doi: 10.5694/mja18.00207.
It is largely unrecognised that the impacts of asthma are different in patients with severe disease compared with patients with mild to moderate disease. Severe asthma is associated with a significant health-related quality of life (HRQoL) burden due to excessive symptoms, frequent and life-threatening attacks, increased comorbidity burden, and high pharmacological treatment requirements. Interventions aimed at improving HRQoL need to be specifically tested in populations with severe asthma, including multicomponent interventions targeting the many clinical characteristics associated with the disease. It is necessary to have patient-reported outcome measures developed specifically for severe asthma. Public health messages recognising the significant burden of severe asthma on quality of life are needed.
人们在很大程度上没有认识到，重症哮喘患者与轻至中度疾病患者的哮喘影响不同。重症哮喘与过度症状、频繁且危及生命的发作、增加的合并症负担以及高药物治疗需求相关，因此与严重的健康相关生活质量（HRQoL）负担有关。旨在改善 HRQoL 的干预措施需要在重症哮喘患者中进行专门测试，包括针对与疾病相关的许多临床特征的多组分干预措施。需要开发专门针对重症哮喘的患者报告结局测量。需要有针对严重哮喘对生活质量造成重大负担的公共卫生信息。
