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肺部非结核分枝杆菌感染的外科治疗

Surgical Treatment of Pulmonary Nontuberculous Mycobacterial Infections.

作者信息

Mitchell John D

机构信息

Section of General Thoracic Surgery, Division of Cardiothoracic Surgery, University of Colorado School of Medicine, Academic Office 1, Room 6602, C-310, 12631 East 17th Avenue, Aurora, CO 80045, USA.

出版信息

Thorac Surg Clin. 2019 Feb;29(1):77-83. doi: 10.1016/j.thorsurg.2018.09.011.

Abstract

Adjuvant surgical resection in the setting of pulmonary nontuberculous mycobacterial (NTM) infection removes focal parenchymal disease thought to serve as a poorly perfused "reservoir" for organisms, thus resistant to standard antimicrobial therapy. Removal of these areas of damaged lung is felt to enhance the effectiveness of the medical treatment. In general, these operations are associated with low morbidity and mortality, although resections that are more extensive carry higher risk. Many of the planned operations may be performed with minimally invasive techniques. More data are needed regarding long-term outcomes in these patients.

摘要

在肺部非结核分枝杆菌(NTM)感染的情况下,辅助性手术切除可去除被认为是细菌灌注不良的“储存库”的局灶性实质病变,因此对标准抗菌治疗具有抗性。切除这些受损肺组织区域被认为可提高药物治疗的效果。一般来说,这些手术的发病率和死亡率较低,尽管范围更广的切除手术风险更高。许多计划中的手术可以采用微创技术进行。需要更多关于这些患者长期预后的数据。

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