• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

推进人体血吸虫病疫苗的发展。

Advancing the Development of a Human Schistosomiasis Vaccine.

机构信息

Texas Children's Hospital Center for Vaccine Development, Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA; Department of Biology, Baylor University, Waco, TX, USA; James A. Baker III Institute of Public Policy, Rice University, Houston, TX, USA.

Texas Children's Hospital Center for Vaccine Development, Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA; Department of Biology, Baylor University, Waco, TX, USA.

出版信息

Trends Parasitol. 2019 Feb;35(2):104-108. doi: 10.1016/j.pt.2018.10.005. Epub 2018 Nov 16.

DOI:10.1016/j.pt.2018.10.005
PMID:30455112
Abstract

Three vaccines against human schistosomiasis are in different phases of clinical development, and a fourth is expected to enter the clinic soon. Successful introduction of an efficacious preventive human schistosomiasis vaccine will require integration into existing health systems such as those that deliver childhood vaccines or mass drug administration programs.

摘要

三种抗人体血吸虫病疫苗处于不同的临床开发阶段,预计第四种疫苗很快将进入临床阶段。成功推出一种有效的预防性人体血吸虫病疫苗,将需要将其纳入现有的卫生系统,如那些提供儿童疫苗或大规模药物管理方案的系统。

相似文献

1
Advancing the Development of a Human Schistosomiasis Vaccine.推进人体血吸虫病疫苗的发展。
Trends Parasitol. 2019 Feb;35(2):104-108. doi: 10.1016/j.pt.2018.10.005. Epub 2018 Nov 16.
2
Sm-p80-Based Schistosomiasis Vaccine: Preparation for Human Clinical Trials.基于Sm-p80的血吸虫病疫苗:人类临床试验准备
Trends Parasitol. 2017 Mar;33(3):194-201. doi: 10.1016/j.pt.2016.10.010. Epub 2016 Nov 16.
3
Quantitative assessment of the impact of partially protective anti-schistosomiasis vaccines.部分保护性抗血吸虫病疫苗影响的定量评估
PLoS Negl Trop Dis. 2017 Apr 14;11(4):e0005544. doi: 10.1371/journal.pntd.0005544. eCollection 2017 Apr.
4
Schistosomiasis vaccines.血吸虫病疫苗
Hum Vaccin. 2011 Nov;7(11):1192-7. doi: 10.4161/hv.7.11.17017. Epub 2011 Nov 1.
5
Advancing a vaccine to prevent human schistosomiasis.推进预防人类血吸虫病的疫苗研发。
Vaccine. 2016 Jun 3;34(26):2988-2991. doi: 10.1016/j.vaccine.2016.03.079. Epub 2016 Mar 29.
6
Human anthelminthic vaccines: Rationale and challenges.人类抗蠕虫疫苗:基本原理与挑战。
Vaccine. 2016 Jun 24;34(30):3549-55. doi: 10.1016/j.vaccine.2016.03.112. Epub 2016 May 9.
7
Can schistosomiasis really be consigned to history without a vaccine?没有疫苗,血吸虫病真的能被彻底消灭吗?
Vaccine. 2008 Jun 25;26(27-28):3373-6. doi: 10.1016/j.vaccine.2008.04.045. Epub 2008 May 7.
8
Vaccine development against neglected tropical diseases.针对被忽视热带病的疫苗研发。
Cad Saude Publica. 2020 Nov 20;36Suppl 2(Suppl 2):e00215720. doi: 10.1590/0102-311X00215720. eCollection 2020.
9
Still hope for schistosomiasis vaccine.血吸虫病疫苗仍有希望。
Hum Vaccin Immunother. 2015;11(10):2504-8. doi: 10.1080/21645515.2015.1059981.
10
Recent advances in proteomic applications for schistosomiasis research: potential clinical impact.血吸虫病研究中蛋白质组学应用的最新进展:潜在的临床影响。
Expert Rev Proteomics. 2017 Feb;14(2):171-183. doi: 10.1080/14789450.2017.1271327. Epub 2016 Dec 22.

引用本文的文献

1
Priority knowledge gaps for schistosomiasis research and development in the World Health Organization Africa Region.世界卫生组织非洲区域血吸虫病研究与发展的重点知识空白。
Infect Dis Poverty. 2025 Mar 17;14(1):19. doi: 10.1186/s40249-025-01285-w.
2
Vaccine value profile for schistosomiasis.血吸虫病疫苗价值概况
Vaccine. 2024 Jul 23:126020. doi: 10.1016/j.vaccine.2024.05.068.
3
Schistosomiasis Chemotherapy, Chemoprevention, and Vaccines: History, Progress, and Priorities.血吸虫病化学疗法、化学预防和疫苗:历史、进展和优先事项。
Immun Inflamm Dis. 2024 Nov;12(11):e70054. doi: 10.1002/iid3.70054.
4
Recent Advances and Methodological Considerations on Vaccine Candidates for Human Schistosomiasis.人类血吸虫病候选疫苗的最新进展与方法学考量
Front Trop Dis. 2021 Aug;2. doi: 10.3389/fitd.2021.719369. Epub 2021 Aug 26.
5
A Journey in Science: Molecular vaccines for global child health in troubled times of anti-science.科学之旅:反科学时代全球儿童健康的分子疫苗
Mol Med. 2024 Mar 15;30(1):37. doi: 10.1186/s10020-024-00786-y.
6
Antigenic epitope targets of rhesus macaques self-curing from infection.从感染中自愈的恒河猴的抗原表位靶点。
Front Immunol. 2024 Feb 23;14:1269336. doi: 10.3389/fimmu.2023.1269336. eCollection 2023.
7
Vaccination against the HDL receptor of S. japonicum inhibits egg embryonation and prevents fatal hepatic complication in rabbit model.接种日本血吸虫高密度脂蛋白受体疫苗可抑制虫卵胚胎发育,防止兔模型中的致命性肝并发症。
PLoS Negl Trop Dis. 2023 Nov 29;17(11):e0011749. doi: 10.1371/journal.pntd.0011749. eCollection 2023 Nov.
8
Trained immunity: a cutting edge approach for designing novel vaccines against parasitic diseases?训练免疫:设计新型寄生虫病疫苗的前沿方法?
Front Immunol. 2023 Oct 6;14:1252554. doi: 10.3389/fimmu.2023.1252554. eCollection 2023.
9
Development of the Sm14/GLA-SE Schistosomiasis Vaccine Candidate: An Open, Non-Placebo-Controlled, Standardized-Dose Immunization Phase Ib Clinical Trial Targeting Healthy Young Women.Sm14/GLA-SE血吸虫病候选疫苗的研发:一项针对健康年轻女性的开放、非安慰剂对照、标准化剂量免疫的Ib期临床试验
Vaccines (Basel). 2022 Oct 15;10(10):1724. doi: 10.3390/vaccines10101724.
10
Malnutrition vaccines for an imminent global food catastrophe.营养不良疫苗应对即将到来的全球粮食灾难。
Trends Pharmacol Sci. 2022 Dec;43(12):994-997. doi: 10.1016/j.tips.2022.08.007. Epub 2022 Sep 10.