Chadolias D, Zissimopoulos A, Nena E, Agathokleous M N, Drakopoulos V, Constantinidis T C, Kouklakis G
Laboratory of Hygiene and Environmental Protection, University General Hospital of Alexandroupolis Medical School, Democritus University of Thrace, Alexandroupolis, Greece.
Nuclear Medicine Department, University General Hospital of Alexandroupolis, University General Hospital of Alexandroupolis Medical School, Democritus University of Thrace, Alexandroupolis, Greece.
Hippokratia. 2017 Apr-Jun;21(2):74-79.
Work is a daily activity with various conditions, exposures, and habits that may affect health either positively or negatively. Aim of this study was to investigate the relationship between occupational factors and conditions, and the occurrence of gastrointestinal disorders.
We enrolled in this study a sample of 891 consecutive individuals, who were examined by standard colonoscopy and gastroscopy and interviewed regarding their working conditions and exposures. Consecutively, data were statistically analyzed to explore possible associations.
Peptic ulcer diagnosis was associated with reports of muscle pain/headache [odds ratio (OR): 3.656, 95 % confidence interval (95% CI): 1.898-7.043], with working in shifts (OR: 2.463, 95% CI: 1.058-5.731), and with the presence of occupational stress (OR: 2.283, 95% CI: 1.162-4.486). Gastritis was associated with muscle pain/headache (OR: 2.258, 95% CI: 1.096-4.652), shift work (OR: 3.535, 95% CI: 1.345-9.29), occupational stress (OR: 2.182, 95% CI: 1.072-4.444), and sedentary work (OR 0.275 lower risk 95% CI: 0.113-0.671). Ulcerative colitis was associated with muscle pain/headache (OR: 6.211, 95% CI: 2.162-17.840) and occupational stress (OR: 6.418, 95% CI: 2.243-18.361), while Crohn's disease diagnosis with muscle pain/headache (OR: 3.554, 95% CI: 1.628-7.759), frequent ordering food at work (OR: 4.928, 95% CI: 2.3-10.559), occupational stress (OR: 3.023, 95% CI: 1.413-6.469), work with intense physical activity (OR: 0.665 lower risk, 95% CI: 0.252-0.758). Colon cancer diagnosis was associated with frequent ordering food at work (OR: 2.739, 95% CI: 1.268-5.916) and occupational stress (OR: 3.175, 95% CI: 1.384-7.286), while stomach cancer diagnosis with ordering food at work (OR: 2.794, 95% CI: 1.154-6.763) and exposure to dust (OR: 5.650, 95% CI: 1.551-20.582). Finally, presence of polyps was associated with ordering food at work (OR: 2.154, 95% CI: 1.135-4.091), and constipation with ordering food at work (OR: 2.869, 95% CI: 1.451-5.672), occupational stress (OR: 2.112, 95% CI: 1.097-4.066), and occupational noise (OR: 0.248, 95% CI: 0.084-0.737).
The incidence of the gastrointestinal diseases is affected by occupational exposures and related lifestyle habits. HIPPOKRATIA 2017, 21(2): 74-79.
工作是一项日常活动，其具有各种条件、暴露因素和习惯，可能对健康产生积极或消极的影响。本研究的目的是调查职业因素与条件和胃肠道疾病发生之间的关系。
我们招募了891名连续的个体作为本研究的样本，他们接受了标准的结肠镜检查和胃镜检查，并就其工作条件和暴露情况接受了访谈。随后，对数据进行统计分析以探索可能的关联。
消化性溃疡的诊断与肌肉疼痛/头痛的报告相关[比值比（OR）：3.656，95%置信区间（95%CI）：1.898 - 7.043]，与轮班工作相关（OR：2.463，95%CI：1.058 - 5.731），以及与职业压力的存在相关（OR：2.283，95%CI：1.162 - 4.486）。胃炎与肌肉疼痛/头痛相关（OR：2.258，95%CI：1.096 - 4.652），轮班工作（OR：3.535，95%CI：1.345 - 9.29），职业压力（OR：2.182，95%CI：1.072 - 4.444），以及久坐工作（OR 0.275，低风险，95%CI：0.113 - 0.671）。溃疡性结肠炎与肌肉疼痛/头痛相关（OR：6.211，95%CI：2.162 - 17.840）和职业压力相关（OR：6.418，95%CI：2.243 - 18.361），而克罗恩病的诊断与肌肉疼痛/头痛相关（OR：3.554，95%CI：1.628 - 7.759），工作时频繁订购食物（OR：4.928，95%CI：2.3 - 10.559），职业压力（OR：3.023，95%CI：1.413 - 6.469），从事高强度体力活动的工作（OR：0.665，低风险，95%CI：0.252 - 0.758）。结肠癌的诊断与工作时频繁订购食物相关（OR：2.739，95%CI：1.268 - 5.916）和职业压力相关（OR：3.175，95%CI：1.384 - 7.286），而胃癌的诊断与工作时订购食物相关（OR：2.794，95%CI：1.154 - 6.763）和接触粉尘相关（OR：5.650，95%CI：1.551 - 20.582）。最后，息肉的存在与工作时订购食物相关（OR：2.154，95%CI：1.135 - 4.091），便秘与工作时订购食物相关（OR：2.869，95%CI：1.451 - 5.672），职业压力（OR：2.112，95%CI：1.097 - 4.066），以及职业噪音相关（OR：0.248，95%CI：0.084 - 0.737）。
胃肠道疾病的发病率受职业暴露和相关生活方式习惯的影响。《希波克拉底》2017年，21(2)：74 - 79。
