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Are Synthetic Data Derivatives the Future of Translational Medicine?合成数据衍生物会是转化医学的未来吗?
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Synthetic Biology and the Translational Imperative.合成生物学与转化的必要性。
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本文引用的文献

1
The Rising Cost of Developing Cardiovascular Therapies and Reproducibility in Translational Research: Do Not Blame It (All) on the Bench.心血管疾病治疗研发成本的上升与转化研究的可重复性:不要(全)归咎于实验台。
JACC Basic Transl Sci. 2017 Oct 30;2(5):627-629. doi: 10.1016/j.jacbts.2017.09.006. eCollection 2017 Oct.
2
The limitations of using randomised controlled trials as a basis for developing treatment guidelines.将随机对照试验作为制定治疗指南基础的局限性。
Evid Based Ment Health. 2018 Feb;21(1):4-6. doi: 10.1136/eb-2017-102701. Epub 2017 Jul 14.
3
A 'green button' for using aggregate patient data at the point of care.一个用于在医疗现场使用患者汇总数据的“绿色按钮”。
Health Aff (Millwood). 2014 Jul;33(7):1229-35. doi: 10.1377/hlthaff.2014.0099.
4
Open science and data sharing in clinical research: basing informed decisions on the totality of the evidence.临床研究中的开放科学与数据共享:基于全部证据做出明智决策。
Circ Cardiovasc Qual Outcomes. 2012 Mar 1;5(2):141-2. doi: 10.1161/CIRCOUTCOMES.112.965848.
5
A pragmatic view on pragmatic trials.关于实用性试验的务实观点。
Dialogues Clin Neurosci. 2011;13(2):217-24. doi: 10.31887/DCNS.2011.13.2/npatsopoulos.
6
The n-of-1 clinical trial: the ultimate strategy for individualizing medicine?n-of-1临床试验:个体化医疗的终极策略?
Per Med. 2011 Mar;8(2):161-173. doi: 10.2217/pme.11.7.
7
An interview with Robert S. Lane, Ph.D. Interviewed by Vicki Glaser.罗伯特·S·莱恩博士访谈录 采访者:维基·格拉泽
Vector Borne Zoonotic Dis. 2010 Mar;10(2):211-5. doi: 10.1089/vbz.2010.1502.
8
Biomedical informatics and outcomes research: enabling knowledge-driven health care.生物医学信息学与结果研究:推动知识驱动型医疗保健
Circulation. 2009 Dec 8;120(23):2393-9. doi: 10.1161/CIRCULATIONAHA.108.795526.
9
Evaluating the state-of-the-art in automatic de-identification.评估自动去识别技术的最新进展。
J Am Med Inform Assoc. 2007 Sep-Oct;14(5):550-63. doi: 10.1197/jamia.M2444. Epub 2007 Jun 28.
10
Practical clinical trials: increasing the value of clinical research for decision making in clinical and health policy.实用临床试验:提高临床研究在临床和卫生政策决策中的价值。
JAMA. 2003 Sep 24;290(12):1624-32. doi: 10.1001/jama.290.12.1624.

Are Synthetic Data Derivatives the Future of Translational Medicine?

作者信息

Foraker Randi, Mann Douglas L, Payne Philip R O

机构信息

Institute for Informatics, Washington University School of Medicine, St. Louis, Missouri.

Center for Cardiovascular Research, Cardiovascular Division, Washington University School of Medicine, St. Louis, Missouri.

出版信息

JACC Basic Transl Sci. 2018 Nov 12;3(5):716-718. doi: 10.1016/j.jacbts.2018.08.007. eCollection 2018 Oct.

DOI:10.1016/j.jacbts.2018.08.007
PMID:30456342
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6234614/
Abstract
摘要