Schachner Thomas, Garrido Fabian, Bonaros Nikolaos, Krapf Christoph, Dumfarth Julia, Grimm Michael
University Clinic of Cardiac Surgery, Innsbruck Medical University, Anichstraße 35, 6020, Innsbruck, Austria.
Wien Klin Wochenschr. 2019 Apr;131(7-8):174-179. doi: 10.1007/s00508-018-1412-2. Epub 2018 Nov 19.
Acute type A aortic dissection (AAD) leads to high hospital mortality rates in the first 48 h after the onset of symptoms. Survivors, however, have good long-term perspectives and enhanced survival especially if regaining moderate amounts of physical activity.
This study analyzed 131 survivors (from 180 consecutive patients, aged 60 years (rande 30-84 years, 71% male) of acute AAD after a median time of 44 months (range 1-147 months). The hospital mortality was 13.5%. The group of physically active patients was compared with those with a sedentary life style. The qualitative and quantitative data on physical activity were correlated with data from an aortic registry.
Overall 87% of patients reported 1 or more types of physical activities after hospital discharge. The most common types were walking (51%), biking (29%), hiking (15%) and gymnastics (14%). Patients with a sedentary life style underwent longer hypothermic circulatory arrest times (39 min, range 8-167 min vs. 47 min, range 27-79 min, p = 0.009), had a longer intensive care unit (ICU) stay (Pearsons r = -0.226 [between length of ICU stay and hours of physical activity after hospital discharge], p = 0.033) and suffered more frequently from postoperative paresis (33.3% vs. 3.8%, p < 0.001) compared with physically active patients. Binary logistic regression analysis showed female gender (p = 0.026) and higher body mass index (p = 0.019) to be independently associated with a reduced amount of physical activity.
This study demonstrate that the majority of survivors of acute aortic dissection type A regain a physically active life including the practice of a variety of sports. Factors predictive of a sedentary life style can be identified. Female patients deserve special attention.
急性A型主动脉夹层(AAD)在症状发作后的最初48小时内导致较高的医院死亡率。然而,幸存者有良好的长期前景且生存率提高,特别是在恢复适量体力活动的情况下。
本研究分析了131例急性A型主动脉夹层幸存者(来自180例连续患者,年龄60岁(范围30 - 84岁,71%为男性),中位时间为44个月(范围1 - 147个月))。医院死亡率为13.5%。将体力活动患者组与久坐生活方式的患者进行比较。体力活动的定性和定量数据与主动脉登记处的数据相关。
总体而言,87%的患者出院后报告进行了1种或更多类型的体力活动。最常见的类型是步行(51%)、骑自行车(29%)、徒步旅行(15%)和体操(14%)。与体力活动患者相比,久坐生活方式的患者经历更长的低温循环停滞时间(39分钟,范围8 - 167分钟对47分钟,范围27 - 79分钟,p = 0.009),重症监护病房(ICU)住院时间更长(皮尔逊相关系数r = -0.226[ICU住院时间与出院后体力活动小时数之间],p = 0.033),术后麻痹发生率更高(33.3%对3.8%,p < 0.001)。二元逻辑回归分析显示女性(p = 0.026)和较高的体重指数(p = 0.019)与体力活动量减少独立相关。
本研究表明,大多数急性A型主动脉夹层幸存者恢复了积极的体力活动生活,包括进行各种运动。可以确定预测久坐生活方式的因素。女性患者值得特别关注。