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急性A型主动脉夹层后限制体力活动的因素。

Factors limiting physical activity after acute type A aortic dissection.

作者信息

Schachner Thomas, Garrido Fabian, Bonaros Nikolaos, Krapf Christoph, Dumfarth Julia, Grimm Michael

机构信息

University Clinic of Cardiac Surgery, Innsbruck Medical University, Anichstraße 35, 6020, Innsbruck, Austria.

出版信息

Wien Klin Wochenschr. 2019 Apr;131(7-8):174-179. doi: 10.1007/s00508-018-1412-2. Epub 2018 Nov 19.

Abstract

BACKGROUND

Acute type A aortic dissection (AAD) leads to high hospital mortality rates in the first 48 h after the onset of symptoms. Survivors, however, have good long-term perspectives and enhanced survival especially if regaining moderate amounts of physical activity.

METHODS

This study analyzed 131 survivors (from 180 consecutive patients, aged 60 years (rande 30-84 years, 71% male) of acute AAD after a median time of 44 months (range 1-147 months). The hospital mortality was 13.5%. The group of physically active patients was compared with those with a sedentary life style. The qualitative and quantitative data on physical activity were correlated with data from an aortic registry.

RESULTS

Overall 87% of patients reported 1 or more types of physical activities after hospital discharge. The most common types were walking (51%), biking (29%), hiking (15%) and gymnastics (14%). Patients with a sedentary life style underwent longer hypothermic circulatory arrest times (39 min, range 8-167 min vs. 47 min, range 27-79 min, p = 0.009), had a longer intensive care unit (ICU) stay (Pearsons r = -0.226 [between length of ICU stay and hours of physical activity after hospital discharge], p = 0.033) and suffered more frequently from postoperative paresis (33.3% vs. 3.8%, p < 0.001) compared with physically active patients. Binary logistic regression analysis showed female gender (p = 0.026) and higher body mass index (p = 0.019) to be independently associated with a reduced amount of physical activity.

CONCLUSIONS

This study demonstrate that the majority of survivors of acute aortic dissection type A regain a physically active life including the practice of a variety of sports. Factors predictive of a sedentary life style can be identified. Female patients deserve special attention.

摘要

背景

急性A型主动脉夹层(AAD)在症状发作后的最初48小时内导致较高的医院死亡率。然而,幸存者有良好的长期前景且生存率提高,特别是在恢复适量体力活动的情况下。

方法

本研究分析了131例急性A型主动脉夹层幸存者(来自180例连续患者,年龄60岁(范围30 - 84岁,71%为男性),中位时间为44个月(范围1 - 147个月))。医院死亡率为13.5%。将体力活动患者组与久坐生活方式的患者进行比较。体力活动的定性和定量数据与主动脉登记处的数据相关。

结果

总体而言,87%的患者出院后报告进行了1种或更多类型的体力活动。最常见的类型是步行(51%)、骑自行车(29%)、徒步旅行(15%)和体操(14%)。与体力活动患者相比,久坐生活方式的患者经历更长的低温循环停滞时间(39分钟,范围8 - 167分钟对47分钟,范围27 - 79分钟,p = 0.009),重症监护病房(ICU)住院时间更长(皮尔逊相关系数r = -0.226[ICU住院时间与出院后体力活动小时数之间],p = 0.033),术后麻痹发生率更高(33.3%对3.8%,p < 0.001)。二元逻辑回归分析显示女性(p = 0.026)和较高的体重指数(p = 0.019)与体力活动量减少独立相关。

结论

本研究表明,大多数急性A型主动脉夹层幸存者恢复了积极的体力活动生活,包括进行各种运动。可以确定预测久坐生活方式的因素。女性患者值得特别关注。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/903b/6459793/5cea6555eed2/508_2018_1412_Fig1_HTML.jpg

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