Department of Radiology ML 5031, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229-3039, USA.
Skeletal Radiol. 2019 Aug;48(8):1289-1291. doi: 10.1007/s00256-018-3114-2. Epub 2018 Nov 20.
An unusual cause of rickets is illustrated by a patient with infantile multisystem inflammatory disease who, by age 2 years and 4 months, developed striking radiographic and clinical rickets restricted to those joints involved by the inflammatory process. The locally increased vascularity from his inflammation led to increased maturation at those sites so rapid as to override the usual enchondral calcification, thus causing a rickets pattern. Other sites, such as the proximal humeri, lacking any inflammation, showed no increased maturation rate and did not manifest local rickets. Rapid local bone maturation may cause localized rickets.
一个不寻常的佝偻病病因是由一名患有婴儿多系统炎症性疾病的患者引起的，该患者在 2 岁零 4 个月时出现了明显的放射性和临床佝偻病，仅局限于炎症过程所涉及的关节。他的炎症导致局部血管增多，这些部位的成熟速度非常快，以至于超过了通常的软骨内钙化，从而导致佝偻病的发生。其他部位，如近端肱骨，没有任何炎症，没有表现出成熟率的增加，也没有出现局部佝偻病。快速的局部骨成熟可能导致局部佝偻病。
