Heidelberg Institute of Global Health, University of Heidelberg, Heidelberg, Germany.
Centre de Recherche en Santé de Nouna, Nouna, Burkina Faso.
Am J Trop Med Hyg. 2019 Jan;100(1):187-191. doi: 10.4269/ajtmh.17-0669.
In this study, we analyze clustering of infant deaths within families living in a rural part of western Burkina Faso. The study included 9,220 infants, born between 1993 and 2009 in Nouna Health and Demographic Surveillance System (HDSS). A clustering of infant deaths in families was explored by calculating observed versus expected number of infant deaths within families for a given family size. In addition, risk ratios were calculated for infant death depending on the vital status of the previous sibling. We observed 470 infant deaths, yielding an overall infant mortality risk of 51/1,000 births. Clustering of infant deaths within families was observed ( = 0.004). In smaller families, the mortality of firstborns was higher than for the following siblings. The infant mortality risk was higher when the preceding sibling died in infancy ( = 0.03). The study supports the hypothesis of infant death clustering existing within rural families in West Africa. Further studies are needed to shed more light on these findings with the goal to develop effective interventions directed toward the families who already lost a child.
在这项研究中,我们分析了生活在布基纳法索西部农村地区的家庭中婴儿死亡的聚集情况。该研究包括了 1993 年至 2009 年间努纳健康和人口监测系统(HDSS)中出生的 9220 名婴儿。通过计算特定家庭规模内家庭中观察到的和预期的婴儿死亡数量,探索了家庭中婴儿死亡的聚集情况。此外,还根据前一个兄弟姐妹的生死状况计算了婴儿死亡的风险比。我们观察到 470 名婴儿死亡,总婴儿死亡率为 51/1000 出生。观察到家庭内婴儿死亡的聚集( = 0.004)。在较小的家庭中,头胎的死亡率高于后续的兄弟姐妹。当前一个兄弟姐妹在婴儿期死亡时,婴儿死亡率更高( = 0.03)。该研究支持了在西非农村家庭中存在婴儿死亡聚集的假设。需要进一步的研究来更深入地了解这些发现,旨在为已经失去孩子的家庭制定有效的干预措施。