Gao Li-Fang, Lin Xin, Hai Xin, Chen Xu-Wei, Wang Jian-Hua
Department of Chemistry, College of Sciences , Northeastern University , Shenyang 110819 , China.
ACS Appl Mater Interfaces. 2018 Dec 12;10(49):43049-43056. doi: 10.1021/acsami.8b15837. Epub 2018 Nov 30.
A highly sensitive and selective detection of p-phenylenediamine (PPD) is achieved by a fluorescence sensor, which is constructed by encapsulating the hydrophobic fluorescent 1-pyrenecarboxaldehyde (Py-CHO) into a polymeric ionic liquid (PIL)-based amphiphilic block copolymer (BCP) micelle. The amine-aldehyde condensation reaction between PPD and Py-CHO leads to the fluorescence quenching of Py-CHO, giving rise to the basis for the quantitative detection of PPD. The core cavity of the micelle formed by the self-assembly of PIL provides an excellent hydrophobic environment for the accommodation of fluorescent Py-CHO, offering significant improved sensitivity and selectivity for PPD detection. The amount of PIL in fabricating the amphiphilic BCP micelle, the BCP-Py-CHO micelle concentration, and the detection pH condition are investigated to obtain the best performance of this sensor. The accurate detection of PPD is achieved in the range of 0.02-10 μmol L under optimal conditions, and the detection limit is 0.007 μmol L (3σ/ s). The developed sensor is successfully applied to the determination of PPD contents in hair dyes, spiked water, and urine samples.
通过一种荧光传感器实现了对对苯二胺（PPD）的高灵敏度和高选择性检测，该传感器是通过将疏水性荧光物质1-芘甲醛（Py-CHO）封装到基于聚合离子液体（PIL）的两亲性嵌段共聚物（BCP）胶束中构建而成。PPD与Py-CHO之间的胺醛缩合反应导致Py-CHO的荧光猝灭，这为PPD的定量检测奠定了基础。由PIL自组装形成的胶束的核心腔为容纳荧光Py-CHO提供了优异的疏水环境，显著提高了PPD检测的灵敏度和选择性。研究了制备两亲性BCP胶束时PIL的用量、BCP-Py-CHO胶束浓度以及检测pH条件，以获得该传感器的最佳性能。在最佳条件下，可在0.02 - 10 μmol/L范围内实现对PPD的准确检测，检测限为0.007 μmol/L（3σ/s）。所开发的传感器已成功应用于染发剂、加标水和尿液样品中PPD含量的测定。
