Nagpal Manish, Mehrotra Navneet, Juneja Rakesh, Vishnoi Avijit, Jain Ashish
Ophthalmic Surg Lasers Imaging Retina. 2018 Nov 1;49(11):859-869. doi: 10.3928/23258160-20181101-07.
To analyze the panorama optical coherence tomography angiography (P-OCTA) characteristics of serpiginous-like choroiditis (SLC) and to correlate these findings with indocyanine green angiography (ICGA).
Prospective, observational study of 32 eyes of 24 patients. Twenty-seven eyes of 16 patients who met inclusion criteria were included in the final study. Multimodal imaging was performed using P-OCTA, OCT, fundus autofluorescence, fluorescein angiography, and ICGA. Morphologic features at the site of lesions were analyzed using P-OCTA and correlated with ICGA.
P-OCTA in active phase revealed areas of large flow void, which correlated with hypofluorescent areas on ICGA. Healing phase revealed appearance of vascular network due unmasking of choriocapillaris that corresponded to reduced hypofluorescence on ICGA.
P-OCTA as a noninvasive tool provides widefield and high-resolution images that can be used as an complementary tool to ICGA for diagnosis of SLC cases. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:859-869.].
分析匐行性脉络膜炎（SLC）的全景光学相干断层扫描血管造影（P-OCTA）特征，并将这些发现与吲哚菁绿血管造影（ICGA）相关联。
对24例患者的32只眼进行前瞻性观察研究。最终研究纳入了16例符合纳入标准患者的27只眼。使用P-OCTA、OCT、眼底自发荧光、荧光素血管造影和ICGA进行多模态成像。利用P-OCTA分析病变部位的形态学特征，并与ICGA相关联。
活动期P-OCTA显示大片血流缺失区域，这与ICGA上的低荧光区域相关。愈合期由于脉络膜毛细血管的显露出现血管网络，这与ICGA上低荧光的减少相对应。
P-OCTA作为一种非侵入性工具，可提供宽视野和高分辨率图像，可作为ICGA的补充工具用于诊断SLC病例。[《眼科手术、激光与视网膜成像》。2018年；49:859 - 869。]
