Bath Jonathan, Dombrovskiy Viktor Y, Vogel Todd R
Division of Vascular Surgery, University of Missouri, School of Medicine, Columbia, MO, USA.
Department of Surgery, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
J Vasc Nurs. 2018 Dec;36(4):189-195. doi: 10.1016/j.jvn.2018.08.002. Epub 2018 Oct 2.
Patient safety is a critical component of health-care quality and measures created by the Agency for Healthcare Research and Quality (AHRQ) to identify hospitalizations with potentially preventable adverse events. This analysis evaluated whether Patient Safety Indicator (PSI) events after open surgical repair (OSR) or endovascular aneurysm repair (EVAR) of abdominal aortic aneurysm (AAA) were associated with increased risk of readmission. Patients undergoing elective repair of nonruptured AAA from 2009 to 2012 were selected in the Medicare Provider Analysis and Review files using the International Classification of Diseases, Ninth Revision, Clinical Modification codes. To identify PSI events, we used the AHRQ PSI International Classification of Diseases, Ninth Revision, Clinical Modification numerator codes. Chi-square test, multivariable logistic regression analysis, nonparametric Wilcoxon rank sum test, and Kaplan-Meier survival analysis were used for statistics. A total of 66,923 patients undergoing elective AAA repair were evaluated: (1) 9,315 with OSR and (2) 57,608 with EVAR. The most frequent PSI events after OSR versus EVAR were postoperative respiratory failure (PSI, 11; 17.7% vs 1.8%; P < .0001); perioperative hemorrhage/hematoma (PSI, 9; 3.6% vs 2.6%; P < .0001); postoperative sepsis (PSI, 13; 3.5% vs 0.4%; P < .0001); accidental puncture or laceration (PSI, 15; 2.1% vs 0.6%; P < .0001); and postoperative acute kidney injury requiring dialysis (PSI, 10; 1.4% vs 0.2%; P < .0001). The overall 30-day readmission rate was 10.5%. The occurrence of any PSI event overall significantly increased 30-day readmission compared with no event cases (odds ratio [OR] = 1.71; 95% confidence interval [CI], 1.57-1.86). Likelihood of 30-day readmission was greater for postoperative acute kidney injury requiring dialysis (OR = 1.66; 95% CI, 1.28-2.15), postoperative respiratory failure (OR = 1.36; 95% CI, 1.22-1.52), perioperative hemorrhage (OR = 1.34; 95% CI, 1.18-1.52), and postoperative pressure ulcer (OR = 2.88; 95% CI, 1.99-4.17). Occurrence of any PSI event was associated with an increased total hospital and intensive care unit length of stay and total hospital charges (all P < .001). In conclusion, AHRQ PSI events may be used to identify patients at the greatest risk for readmission after AAA repair. The risk for 30-day readmission was 71% higher when a PSI event occurred and was not associated with the type of repair. Minimizing preventable PSI events may be beneficial to reducing hospital readmissions after open and endovascular AAA repair and to improving hospital resource utilization.
患者安全是医疗质量的关键组成部分,医疗保健研究与质量局(AHRQ)制定了相关措施来识别可能存在可预防不良事件的住院情况。本分析评估了腹主动脉瘤(AAA)开放手术修复(OSR)或血管内动脉瘤修复(EVAR)后患者安全指标(PSI)事件是否与再入院风险增加相关。利用国际疾病分类第九版临床修订本编码,在医疗保险提供者分析与审查文件中选取了2009年至2012年接受非破裂性AAA择期修复的患者。为识别PSI事件,我们使用了AHRQ PSI国际疾病分类第九版临床修订本分子编码。采用卡方检验、多变量逻辑回归分析、非参数Wilcoxon秩和检验以及Kaplan-Meier生存分析进行统计。总共评估了66923例接受AAA择期修复的患者:(1)9315例接受OSR,(2)57608例接受EVAR。OSR与EVAR后最常见的PSI事件分别为术后呼吸衰竭(PSI,11;17.7%对1.8%;P <.0001);围手术期出血/血肿(PSI,9;3.6%对2.6%;P <.0001);术后脓毒症(PSI,13;3.5%对0.4%;P <.0001);意外穿刺或撕裂伤(PSI,15;2.1%对0.6%;P <.0001);以及需要透析的术后急性肾损伤(PSI,10;1.4%对0.2%;P <.0001)。总体30天再入院率为10.5%。与无事件病例相比,任何PSI事件的发生总体上显著增加了30天再入院率(比值比[OR]=1.71;95%置信区间[CI],1.57 - 1.86)。需要透析的术后急性肾损伤(OR = 1.66;95% CI,1.28 - 2.15)、术后呼吸衰竭(OR = 1.36;95% CI,1.22 - 1.52)、围手术期出血(OR = 1.34;95% CI,1.18 - 1.52)以及术后压疮(OR = 2.88;95% CI,1.99 - 4.17)的30天再入院可能性更大。任何PSI事件的发生都与总住院时间和重症监护病房住院时间增加以及总住院费用增加相关(所有P <.001)。总之,AHRQ PSI事件可用于识别AAA修复后再入院风险最高的患者。当发生PSI事件时,30天再入院风险高出71%,且与修复类型无关。将可预防的PSI事件降至最低可能有助于减少开放和血管内AAA修复后的医院再入院率,并改善医院资源利用。