Lawson G H, McOrist S, Rowland A C, McCartney E, Roberts L
Department of Veterinary Pathology, Royal (Dick) School of Veterinary Studies, Edinburgh University, Easter Bush, Roslin.
Vet Rec. 1988 Jun 4;122(23):554-7. doi: 10.1136/vr.122.23.554.
Campylobacter mucosalis and C hyointestinalis have been associated with the proliferative enteropathies of pigs. An examination of the antibody response to these organisms and to the intracellular campylobacter-like organism was undertaken. Antibody to the campylobacter-like organism was predominantly IgM, short lived, and could be detected by an immunofluorescence test using bacteria released from lesions as antigen. The majority (75 per cent) of pigs with proliferative enteropathy at necropsy were antibody positive and a small number (4 per cent) of pigs in which lesions were not observed were found to have antibody. Antibody appeared to be correlated with the presence of lesions rather than with exposure to infection and was independent of the presence of antibody to C mucosalis or C hyointestinalis. In natural outbreaks of the disease antibody to the campylobacter-like organism was more prevalent than clinical signs in the affected animals.
黏膜弯曲杆菌和猪肠弯曲杆菌与猪的增生性肠病有关。对这些微生物以及细胞内类弯曲杆菌微生物的抗体反应进行了检测。针对类弯曲杆菌微生物的抗体主要为IgM,持续时间短,可通过使用从病变部位释放的细菌作为抗原的免疫荧光试验检测到。尸检时患有增生性肠病的猪中,大多数(75%)抗体呈阳性,而在未观察到病变的猪中,有少数(4%)被发现有抗体。抗体似乎与病变的存在相关,而非与接触感染相关,并且与针对黏膜弯曲杆菌或猪肠弯曲杆菌的抗体存在无关。在该疾病的自然爆发中,受感染动物体内针对类弯曲杆菌微生物的抗体比临床症状更为普遍。