Wang Hui, Kang Di, Zhou Xue-Dong, Li Yu-Qing
State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Hua Xi Kou Qiang Yi Xue Za Zhi. 2018 Oct 1;36(5):564-567. doi: 10.7518/hxkq.2018.05.018.
The microbe is small in volume, but large in quantity and species. The symbiotic microbe, which is far more than human cells, code millions times of genes than human being. Somatic cells and these symbiotic microbe distributing in human body skin, respiratory tract, oral cavity and gastrointestinal tract, urinary tract and other parts form a complex ecosystem whose dynamic balance is highly related to body health. With the successful implementation of Human Microbiome Project, more attentions have been paid to the next generation microbiome technologies. New tools and methods for ecological regulation of human microbiome are emerging. The way we improve the world of human microbiology will be more convenient. This paper will make a review on the modulation techniques of human microbiome.
微生物体积小，但数量和种类繁多。共生微生物的数量远远超过人体细胞，其编码的基因数量是人类的数百万倍。分布在人体皮肤、呼吸道、口腔、胃肠道、泌尿道等部位的体细胞和这些共生微生物形成了一个复杂的生态系统，其动态平衡与身体健康高度相关。随着人类微生物组计划的成功实施，人们对下一代微生物组技术给予了更多关注。用于人类微生物组生态调节的新工具和方法不断涌现。我们改善人类微生物世界的方式将更加便捷。本文将对人类微生物组的调控技术进行综述。
