Hirata Yukina, Kusunose Kenya, Yamada Hirotsugu, Morita Sae, Torii Yuta, Nishio Susumu, Zheng Robert, Saijo Yoshihito, Fukuda Daiju, Yagi Shusuke, Soeki Takeshi, Sata Masataka
Ultrasound Examination Center, Tokushima University Hospital, Tokushima, Japan.
Department of Cardiovascular Medicine, Tokushima University Hospital, 2-50-1 Kuramoto, Tokushima, Japan.
Int J Cardiovasc Imaging. 2019 Apr;35(4):633-643. doi: 10.1007/s10554-018-1502-2. Epub 2018 Nov 23.
Middle-aged marathon runners have an increased risk of developing atrial fibrillation (AF). A previous study described that repetitive marathon running was associated with left atrial (LA) dysfunction. However, whether this change is common in marathon runners and which runners are at risk of LA dysfunction remain unknown. The purpose of this study was to determine which factors could predict LA dysfunction. We prospectively examined 12 healthy amateur volunteers (9 males, 31 ± 8 years old) who participated in a full marathon. All echocardiographic measurements and speckle-tracking echocardiography were performed before and after the marathon. The endpoint was defined as reduced LA reservoir strain 1 day after the marathon (non-responder group). Seven participants were in the non-responder group. Age (35 ± 9 vs. 26 ± 2 years, p = 0.020), augmentation index (76 ± 12 vs. 55 ± 8, p = 0.002), and diastolic blood pressures (83 ± 11 vs. 70 ± 7 mmHg, p = 0.021) in the non-responder group were significantly higher compared with the responder group. In multivariate linear regression analysis, only the augmentation index was an independent predictor of reduced LA reservoir function after the marathon (β = - 0.646, p = 0.023). The augmentation index was a predictive marker for reduction in LA reservoir function after a marathon in healthy amateur volunteers.
中年马拉松跑者患心房颤动（AF）的风险增加。先前的一项研究表明，反复参加马拉松跑步与左心房（LA）功能障碍有关。然而，这种变化在马拉松跑者中是否常见以及哪些跑者有LA功能障碍的风险仍然未知。本研究的目的是确定哪些因素可以预测LA功能障碍。我们前瞻性地检查了12名参加全程马拉松的健康业余志愿者（9名男性，31±8岁）。在马拉松比赛前后均进行了所有超声心动图测量和斑点追踪超声心动图检查。终点定义为马拉松比赛后1天左心房储备应变降低（无反应组）。7名参与者属于无反应组。与有反应组相比，无反应组的年龄（35±9岁对26±2岁，p = 0.020）、增强指数（76±12对55±8，p = 0.002）和舒张压（83±11对70±7 mmHg，p = 0.021）显著更高。在多变量线性回归分析中，只有增强指数是马拉松比赛后左心房储备功能降低的独立预测因子（β = -0.646，p = 0.023）。增强指数是健康业余志愿者马拉松比赛后左心房储备功能降低的预测指标。
