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内镜超声引导下胆道引流术治疗不可切除的肝门部恶性胆管梗阻

Endoscopic Ultrasound-Guided Biliary Drainage for Unresectable Hilar Malignant Biliary Obstruction.

作者信息

Nakai Yousuke, Kogure Hirofumi, Isayama Hiroyuki, Koike Kazuhiko

机构信息

Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Japan.

Department of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.

出版信息

Clin Endosc. 2019 May;52(3):220-225. doi: 10.5946/ce.2018.094. Epub 2018 Nov 29.

DOI:10.5946/ce.2018.094
PMID:30472818
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6547346/
Abstract

Endoscopic transpapillary biliary drainage is the current standard of care for unresectable hilar malignant biliary obstruction (MBO) and bilateral metal stent placement is shown to have longer patency. However, technical and clinical failure is possible and percutaneous transhepatic biliary drainage (PTBD) is sometimes necessary. Endoscopic ultrasound-guided biliary drainage (EUS-BD) is increasingly being reported as an alternative rescue procedure to PTBD. EUS-BD has a potential advantage of not traversing the biliary stricture and internal drainage can be completed in a single session. Some approaches to bilateral biliary drainage for hilar MBO under EUS-guidance include a bridging method, hepaticoduodenostomy, and a combination of EUS-BD and transpapillary biliary drainage. The aim of this review is to summarize data on EUS-BD for hilar MBO and to clarify its advantages over the conventional approaches such as endoscopic transpapillary biliary drainage and PTBD.

摘要

内镜下经乳头胆管引流术是目前不可切除肝门部恶性胆管梗阻(MBO)的标准治疗方法,且已证实双侧金属支架置入的通畅时间更长。然而,该技术和临床治疗仍可能失败,有时需要行经皮经肝胆管引流术(PTBD)。越来越多的报道称,内镜超声引导下胆管引流术(EUS-BD)可作为PTBD的替代补救方法。EUS-BD的潜在优势在于不穿过胆管狭窄部位,且可在一次手术中完成内引流。在EUS引导下对肝门部MBO进行双侧胆管引流的一些方法包括桥接法、肝十二指肠吻合术以及EUS-BD与经乳头胆管引流术联合应用。本综述的目的是总结关于EUS-BD治疗肝门部MBO的数据,并阐明其相对于内镜下经乳头胆管引流术和PTBD等传统方法的优势。

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本文引用的文献

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EUS-guided Biliary Drainage for Malignant Perihilar Biliary Strictures after Further Transpapillary Intervention Has Been Judged to Be Impossible or Ineffective.经内镜超声引导下胆管引流术用于经乳头进一步干预被判定为不可能或无效的恶性肝门部胆管狭窄。
Intern Med. 2017 Dec 1;56(23):3145-3151. doi: 10.2169/internalmedicine.9001-17. Epub 2017 Oct 11.
2
Is EUS-guided drainage a suitable alternative technique in case of proximal biliary obstruction?对于近端胆管梗阻,超声内镜引导下引流是否是一种合适的替代技术?
Therap Adv Gastroenterol. 2017 Jul;10(7):537-544. doi: 10.1177/1756283X17702614. Epub 2017 Apr 20.
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Recent advances in endoscopic ultrasound-guided biliary drainage.
Endoscopic treatment of unresectable perihilar cholangiocarcinoma: beyond biliary drainage.不可切除性肝门部胆管癌的内镜治疗:超越胆道引流
Therap Adv Gastroenterol. 2025 Apr 14;18:17562848251328595. doi: 10.1177/17562848251328595. eCollection 2025.
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Efficacy and safety of endoscopic ultrasound-guided hepaticogastrostomy for biliary drainage in hypervascular hepatocellular carcinoma: a retrospective study from Japan.超声内镜引导下肝胃吻合术用于富血管性肝细胞癌胆道引流的疗效及安全性:来自日本的一项回顾性研究
Clin Endosc. 2025 May;58(3):448-456. doi: 10.5946/ce.2024.079. Epub 2024 Nov 11.
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Defining failure of endoluminal biliary drainage in the era of endoscopic ultrasound and lumen apposing metal stents.在超声内镜和腔内贴合金属支架时代定义内镜下胆道引流失败。
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