Mahmud Sarbast A, Al-Habib Omar A M, Bugonl Serena, Clericuzio Marco, Vidari Giovanni
Nat Prod Commun. 2016 Nov;11(11):1637-1639.
A new ursane-type triterpene acid, named azarolic acid (1), along with four known phenolic compounds and four known triterpene acids, was isolated from the crude EtOAc extract of the leaves of Crataegus azarolus var. aronia L. The structure of 1 was determined from 1D and 2D NMR spectroscopic data. Euscaphic acid showed high anti-vasoconstriction effects on aortic rings, supporting the use of this medicinal plant in cardiovascular disease.
从沙棘山楂变种（Crataegus azarolus var. aronia L.）叶片的乙酸乙酯粗提物中分离出一种新的乌苏烷型三萜酸，命名为azarolic酸（1），以及四种已知的酚类化合物和四种已知的三萜酸。通过一维和二维核磁共振光谱数据确定了1的结构。野鸦椿酸对主动脉环显示出高抗血管收缩作用，这支持了这种药用植物在心血管疾病中的应用。
