Zhou Yanming, Hu Bin, Wei Kongyuan, Si Xiaoying
Department of Hepatobiliary & Pancreatovascular Surgery, First affiliated Hospital of Xiamen University, Xiamen, China.
Department of Clinical Laboratory Medicine, First affiliated Hospital of Xiamen University, Xiamen, China.
BMC Gastroenterol. 2018 Nov 26;18(1):176. doi: 10.1186/s12876-018-0909-5.
Delayed gastric emptying (DGE) is one of the most frequent complications following pancreaticoduodenectomy. This meta-analysis aimed to evaluate the impact of Braun enteroenterostomy on DGE following pancreaticoduodenectomy.
A systematic review of the literature was performed to identify relevant studies. Statistical analysis was carried out using Review Manager software 5.3.
Eleven studies involving 1672 patients (1005 in Braun group and 667 in non-Braun group) were included in the meta-analysis. Braun enteroenterostomy was associated with a statistically significant reduction in overall DGE (odds ratios [OR] 0.32, 95% confidence intervals [CI] 0.24 to 0.43; P <0.001), clinically significant DGE (OR 0.27, 95% CI 0.15 to 0.51; P <0.001), bile leak (OR 0.50, 95% CI 0.29 to 0.86; P = 0.01), and length of hospital stay (weighted mean difference -1.66, 95% CI -2.95 to 00.37; P = 0.01).
Braun enteroenterostomy minimizes the rate and severity of DGE following pancreaticoduodenectomy.
胃排空延迟（DGE）是胰十二指肠切除术后最常见的并发症之一。本荟萃分析旨在评估 Braun 肠肠吻合术对胰十二指肠切除术后 DGE 的影响。
对文献进行系统回顾以确定相关研究。使用 Review Manager 软件 5.3 进行统计分析。
荟萃分析纳入了 11 项研究，共 1672 例患者（Braun 组 1005 例，非 Braun 组 667 例）。Braun 肠肠吻合术与总体 DGE 的统计学显著降低相关（优势比[OR]0.32，95%置信区间[CI]0.24 至 0.43；P<0.001），临床显著 DGE（OR 0.27，95%CI 0.15 至 0.51；P<0.001），胆漏（OR 0.50，95%CI 0.29 至 0.86；P = 0.01），以及住院时间（加权平均差 -1.66，95%CI -2.95 至 -0.37；P = 0.01）。
Braun 肠肠吻合术可使胰十二指肠切除术后 DGE 的发生率和严重程度降至最低。
