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家畜 2.0 - 为更健康、更有活力、更高产的养殖动物进行基因组编辑。

Livestock 2.0 - genome editing for fitter, healthier, and more productive farmed animals.

机构信息

The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.

出版信息

Genome Biol. 2018 Nov 26;19(1):204. doi: 10.1186/s13059-018-1583-1.

DOI:10.1186/s13059-018-1583-1
PMID:30477539
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6258497/
Abstract

The human population is growing, and as a result we need to produce more food whilst reducing the impact of farming on the environment. Selective breeding and genomic selection have had a transformational impact on livestock productivity, and now transgenic and genome-editing technologies offer exciting opportunities for the production of fitter, healthier and more-productive livestock. Here, we review recent progress in the application of genome editing to farmed animal species and discuss the potential impact on our ability to produce food.

摘要

人口在增长,因此我们需要在减少农业对环境影响的同时增加粮食产量。选择性育种和基因组选择对牲畜生产力产生了变革性的影响,而现在转基因和基因组编辑技术为生产更健康、更有生产力的牲畜提供了令人兴奋的机会。在这里,我们回顾了基因组编辑在养殖动物物种中的应用的最新进展,并讨论了其对我们生产食物的能力的潜在影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/addc/6258497/75c7cc2fe4d9/13059_2018_1583_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/addc/6258497/75c7cc2fe4d9/13059_2018_1583_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/addc/6258497/75c7cc2fe4d9/13059_2018_1583_Fig1_HTML.jpg

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