Velter C
Service de dermatologie, institut Gustave-Roussy, 94805 Villejuif, France.
Ann Dermatol Venereol. 2018 Nov;145 Suppl 5:VS30-VS35. doi: 10.1016/S0151-9638(18)31256-0.
Radiotherapy is an available but not well-known treatment for management of basal cell carcinoma. National organizations have established that standard therapy is complete surgical removal and radiation therapy is an option for inoperable tumors or those where the post-operative defect would be cosmetically disfiguring or functionally disabling. These therapeutic options, with histological sample, should be considered in the multidisciplinary management of patients with basal cell carcinoma. There are several types of radiotherapy: external radiation or interstitial brachytherapy, unfortunately, there is no consensus in the literature and the range of radiation regimens in common use is large. Very few randomized studies have been conducted to defi the optimum treatment in terms of recurrence rate, cosmetic outcome and side-eff In most of studies, the overall local control rate was between 80-100% and over 90% of patients reported good or excellent cosmetic outcome. Side-eff of radiotherapy most commonly reported are minor but in young patients one must be alert to the theoretical possibility of the induction of secondary malignancies. Cet article fait partie du numéro supplément Prise en charge des carcinomes basocellulaires difficiles à traiter réalisé avec le soutien institutionnel de Sun Pharma.
放射治疗是一种可用于治疗基底细胞癌但并不广为人知的方法。国家组织已确定标准治疗方法是完整的手术切除，而放射治疗是无法手术切除的肿瘤或术后缺损会在美容上造成毁容或功能丧失的肿瘤的一种选择。在基底细胞癌患者的多学科管理中，应结合组织学样本考虑这些治疗选择。放射治疗有几种类型：外照射或组织间近距离放射治疗，不幸的是，文献中尚无共识，常用的放射治疗方案范围很广。很少有随机研究来确定在复发率、美容效果和副作用方面的最佳治疗方法。在大多数研究中，总体局部控制率在80%至100%之间，超过90%的患者报告美容效果良好或极佳。最常报告的放射治疗副作用较小，但对于年轻患者，必须警惕诱发继发性恶性肿瘤的理论可能性。本文是在太阳制药公司的机构支持下完成的关于难治性基底细胞癌治疗的增刊的一部分。
