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睡眠呼吸障碍且呼吸暂停低通气指数(AHI)<5的患者在药物诱导睡眠内镜检查中的上气道阻塞模式

Patterns of Upper Airway Obstruction on Drug-Induced Sleep Endoscopy in Patients with Sleep-Disordered Breathing with AHI <5.

作者信息

Spinowitz Sam, Kim Mimi, Park Steven Y

机构信息

Department of Otolaryngology-Head and Neck Surgery, Montefiore Medical Center, Bronx, New York, USA.

Department of Epidemiology and Population Health at the Albert Einstein College of Medicine, Bronx, New York, USA.

出版信息

OTO Open. 2017 Aug 29;1(3):2473974X17721483. doi: 10.1177/2473974X17721483. eCollection 2017 Jul-Sep.

Abstract

OBJECTIVE

To describe the patterns of upper airway obstruction in patients with sleep-disordered breathing with apnea-hypopnea index (AHI) <5 using drug-induced sleep endoscopy (DISE).

STUDY DESIGN

Retrospective study.

SETTING

Tertiary care center.

SUBJECTS AND METHODS

Inclusion of patients with sleep-disordered breathing with AHI <5 on polysomnography who underwent DISE. Patients <18 years of age were excluded. DISE findings were reported with the VOTEL classification system: the level of collapse was described as occurring at the velum, oropharynx, tongue base, epiglottis, and the lingual tonsils. The degree of collapse was reported as complete, partial, or none. The pattern of the obstruction was described as anteroposterior, lateral, or concentric when applicable.

RESULTS

A total of 54 patients with sleep-disordered breathing with AHI <5 underwent DISE. Ages ranged from 19 to 65 years. DISE was performed alone in 7% (n = 4) of patients and in conjunction with surgery in 93% (n = 50) of patients. The velum was the most frequent site of upper airway obstruction (85%, n = 46), followed by base of tongue (63%, n = 34), epiglottis (39%, n = 21), lingual tonsils (35%, n = 19), and oropharynx (31%, n = 17). Eighty-three percent (n = 45) of patients had multiple levels of upper airway obstruction, and 15% (n = 8) had a single level of upper airway obstruction.

CONCLUSION

Patients with sleep-disordered breathing with AHI <5 have significant upper airway obstruction as seen on DISE. DISE findings indicate that a majority of these patients have multiple levels of upper airway obstruction, which can lead to significant symptoms.

摘要

目的

使用药物诱导睡眠内镜检查(DISE)描述呼吸暂停低通气指数(AHI)<5的睡眠呼吸障碍患者的上气道阻塞模式。

研究设计

回顾性研究。

研究地点

三级医疗中心。

研究对象与方法

纳入多导睡眠图显示AHI<5且接受DISE检查的睡眠呼吸障碍患者。排除年龄<18岁的患者。DISE检查结果采用VOTEL分类系统报告:塌陷水平描述为发生在软腭、口咽、舌根、会厌和舌扁桃体处。塌陷程度报告为完全、部分或无。适用时,阻塞模式描述为前后位、侧位或同心位。

结果

共有54例AHI<5的睡眠呼吸障碍患者接受了DISE检查。年龄范围为19至65岁。7%(n=4)的患者单独进行DISE检查,93%(n=50)的患者DISE检查与手术联合进行。软腭是上气道阻塞最常见的部位(85%,n=46),其次是舌根(63%,n=34)、会厌(39%,n=21)、舌扁桃体(35%,n=19)和口咽(31%,n=17)。83%(n=45)的患者存在多个上气道阻塞水平,15%(n=8)的患者存在单个上气道阻塞水平。

结论

DISE检查显示,AHI<5的睡眠呼吸障碍患者存在明显的上气道阻塞。DISE检查结果表明,这些患者中的大多数存在多个上气道阻塞水平,这可能导致明显的症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41b3/6239036/e4f4727ae2c7/10.1177_2473974X17721483-fig1.jpg

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