相似文献
1
PARP family enzymes: regulation and catalysis of the poly(ADP-ribose) posttranslational modification.
Curr Opin Struct Biol. 2018 Dec;53:187-198. doi: 10.1016/j.sbi.2018.11.002. Epub 2018 Nov 24.
2
Poly(ADP-ribose) polymerase enzymes and the maintenance of genome integrity.
Cell Mol Life Sci. 2020 Jan;77(1):19-33. doi: 10.1007/s00018-019-03366-0. Epub 2019 Nov 21.
3
Regulation of PARP1/2 and the tankyrases: emerging parallels.
Biochem J. 2024 Sep 4;481(17):1097-1123. doi: 10.1042/BCJ20230230.
4
Functional characterization of the poly(ADP-ribose) polymerase activity of tankyrase 1, a potential regulator of telomere length.
J Mol Biol. 2002 Oct 18;323(2):217-24. doi: 10.1016/s0022-2836(02)00946-4.
5
PARP Power: A Structural Perspective on PARP1, PARP2, and PARP3 in DNA Damage Repair and Nucleosome Remodelling.
Int J Mol Sci. 2021 May 12;22(10):5112. doi: 10.3390/ijms22105112.
6
Poly (ADP-Ribose) Polymerases (PARPs) and PARP Inhibitor-Targeted Therapeutics.
Anticancer Agents Med Chem. 2019;19(2):206-212. doi: 10.2174/1871520618666181109164645.
7
Tankyrases as drug targets.
FEBS J. 2013 Aug;280(15):3576-93. doi: 10.1111/febs.12320. Epub 2013 Jun 18.
8
Tankyrase-targeted therapeutics: expanding opportunities in the PARP family.
Nat Rev Drug Discov. 2012 Dec;11(12):923-36. doi: 10.1038/nrd3868.
9
Poly(ADP-ribose) polymerase-1 activation during DNA damage and repair.
Methods Enzymol. 2006;409:493-510. doi: 10.1016/S0076-6879(05)09029-4.
10
Generating Protein-Linked and Protein-Free Mono-, Oligo-, and Poly(ADP-Ribose) In Vitro.
Methods Mol Biol. 2018;1813:91-108. doi: 10.1007/978-1-4939-8588-3_7.
引用本文的文献
1
Combination Therapy Using Phytochemicals and PARP Inhibitors in Hybrid Nanocarriers: An Optimistic Approach for the Management of Colon Cancer.
Int J Mol Sci. 2025 Jul 30;26(15):7350. doi: 10.3390/ijms26157350.
2
The linker histone chaperone Prothymosin α (PTMA) is essential for efficient DNA damage repair and the recruitment of PARP1.
Epigenetics Chromatin. 2025 Jun 5;18(1):32. doi: 10.1186/s13072-025-00599-1.
3
Widespread false negatives in DNA-encoded library data: how linker effects impair machine learning-based lead prediction.
Chem Sci. 2025 May 9. doi: 10.1039/d5sc00844a.
4
NUDT16 enhances the resistance of cancer cells to DNA-damaging agents by regulating replication fork stability via reversing HMGA1 ADP-ribosylation.
J Biol Chem. 2025 Apr 25;301(6):108551. doi: 10.1016/j.jbc.2025.108551.
5
FTO suppresses DNA repair by inhibiting PARP1.
Nat Commun. 2025 Mar 25;16(1):2925. doi: 10.1038/s41467-025-58309-0.
6
Poly ADP-Ribosylation in a Plant Pathogenic Oomycete : A Key Controller of Growth and Host Plant Colonisation.
J Fungi (Basel). 2025 Jan 3;11(1):29. doi: 10.3390/jof11010029.
7
Subcellular NAD pools are interconnected and buffered by mitochondrial NAD.
Nat Metab. 2024 Dec;6(12):2319-2337. doi: 10.1038/s42255-024-01174-w. Epub 2024 Dec 13.
8
Prospects for PARG inhibitors in cancer therapy.
J Mol Cell Biol. 2025 May 22;16(11). doi: 10.1093/jmcb/mjae050.
9
Discovery of PARP1-Sparing Inhibitors for Protein ADP-Ribosylation.
ACS Med Chem Lett. 2024 Oct 30;15(11):1940-1946. doi: 10.1021/acsmedchemlett.4c00395. eCollection 2024 Nov 14.
10
An NAD with Dually Modified Adenine for Labeling ADP-Ribosylation-Specific Proteins.
Tetrahedron. 2024 Dec 1;168. doi: 10.1016/j.tet.2024.134361. Epub 2024 Nov 6.
本文引用的文献
1
Structural basis for DNA break recognition by ARTD2/PARP2.
Nucleic Acids Res. 2018 Dec 14;46(22):12154-12165. doi: 10.1093/nar/gky927.
2
The comings and goings of PARP-1 in response to DNA damage.
DNA Repair (Amst). 2018 Nov;71:177-182. doi: 10.1016/j.dnarep.2018.08.022. Epub 2018 Aug 23.
3
Systems-wide Analysis of Serine ADP-Ribosylation Reveals Widespread Occurrence and Site-Specific Overlap with Phosphorylation.
Cell Rep. 2018 Aug 28;24(9):2493-2505.e4. doi: 10.1016/j.celrep.2018.07.083.
4
Poly(ADP-ribose) polymerase 1 searches DNA via a 'monkey bar' mechanism.
Elife. 2018 Aug 8;7:e37818. doi: 10.7554/eLife.37818.
5
Regulation of tankyrase activity by a catalytic domain dimer interface.
Biochem Biophys Res Commun. 2018 Sep 10;503(3):1780-1785. doi: 10.1016/j.bbrc.2018.07.113. Epub 2018 Jul 26.
6
Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance.
Nat Commun. 2018 May 10;9(1):1849. doi: 10.1038/s41467-018-03917-2.
7
NAD analog reveals PARP-1 substrate-blocking mechanism and allosteric communication from catalytic center to DNA-binding domains.
Nat Commun. 2018 Feb 27;9(1):844. doi: 10.1038/s41467-018-03234-8.
8
Serine is the major residue for ADP-ribosylation upon DNA damage.
Elife. 2018 Feb 26;7:e34334. doi: 10.7554/eLife.34334.
9
PARP1 changes from three-dimensional DNA damage searching to one-dimensional diffusion after auto-PARylation or in the presence of APE1.
Nucleic Acids Res. 2017 Dec 15;45(22):12834-12847. doi: 10.1093/nar/gkx1047.
10
Specificity of reversible ADP-ribosylation and regulation of cellular processes.
Crit Rev Biochem Mol Biol. 2018 Feb;53(1):64-82. doi: 10.1080/10409238.2017.1394265. Epub 2017 Nov 3.
Zotero 插件