Kardjati S, Kusin J A, De With C
Nutrition Laboratory, School of Medicine, Airlangga University, Surabaya, Indonesia.
Br J Obstet Gynaecol. 1988 Aug;95(8):783-94. doi: 10.1111/j.1471-0528.1988.tb06553.x.
The effect of two levels of energy supplementation in the last trimester of pregnancy on birthweight was tested in a controlled randomized trial in three villages in Madura, East Java. The high and low energy supplements provided 1.95 MJ (465 kcal) and 218 kJ (52 kcal) per day respectively. In the baseline period the home diet provided on average 6.28 MJ (1500 kcal) (SD 2.1 MJ (499 kcal] and 41 g (SD 13 g) of protein. The mean birthweight was 2835 g and the rate of low birthweight 12.2%. In the experimental period the home diet was better. The average intake ranged from 6.45 to 7.19 MJ (1541-1717 kcal) and 41.4-44.2 g per day, depending on the degree of compliance. Mean birthweight increased by 100 g and the rate of low birthweight dropped to 9.5%. There was no difference between the high and low energy supplemented group as a whole, probably due to the masking effect of the better home diet in the experimental period. It is likely that a positive effect of energy supplementation on birthweight was restricted to the group of pregnant women with the lowest home dietary intake and/or a low prepregnant weight. In this community targeting of supplementation to lean seasons and/or to women with a low prepregnant weight may be cost-effective.
在东爪哇马都拉的三个村庄进行的一项对照随机试验中,测试了孕期最后三个月两种能量补充水平对出生体重的影响。高能量补充剂和低能量补充剂分别每天提供1.95兆焦耳(465千卡)和218千焦耳(52千卡)。在基线期,家庭饮食平均提供6.28兆焦耳(1500千卡)(标准差2.1兆焦耳(499千卡))和41克(标准差13克)蛋白质。平均出生体重为2835克,低出生体重率为12.2%。在实验期,家庭饮食有所改善。根据依从程度,平均摄入量在每天6.45至7.19兆焦耳(1541 - 1717千卡)和41.4 - 44.2克之间。平均出生体重增加了100克,低出生体重率降至9.5%。总体而言,高能量补充组和低能量补充组之间没有差异,这可能是由于实验期家庭饮食改善的掩盖作用。能量补充对出生体重的积极影响可能仅限于家庭饮食摄入量最低和/或孕前体重较低的孕妇群体。在这个社区,将补充剂的目标人群定为淡季和/或孕前体重较低的妇女可能具有成本效益。