a Discipline of Physiotherapy , La Trobe University , Melbourne , Victoria , Australia.
b Institute for Breathing and Sleep , Melbourne , Australia.
Expert Rev Respir Med. 2019 Jan;13(1):13-22. doi: 10.1080/17476348.2019.1552833. Epub 2018 Nov 30.
: Regular exercise and physical activity participation are recommended in guideline-based care for individuals with cystic fibrosis (CF) across the spectrum of age and disease severity. However, the best training methods to improve physical function and encourage ongoing exercise and activity participation are not clear, which is an ongoing challenge for clinicians. : This perspective provides an overview of current evidence for exercise and physical activity relative to clinical outcomes and health-care utilization in people with CF, and highlights areas of future research need. : What kind, how much, how often, and how best to support people with CF to be physically active is uncertain. Whether new methods of training, the use of technology, or pharmaceutical developments could best deliver increased activity and physiological benefit without increased therapeutic burden is unclear. At present, if people with CF are going to be physically active, seemingly they should aim to perform this activity in the way most likely to confer some health benefit i.e. concerted exercise bouts of at least 10 min in addition to any incidental (habitual) activity performed during the course of daily life.
：在基于指南的囊性纤维化（CF）个体护理中，建议进行有规律的运动和身体活动。然而，改善身体功能、鼓励持续运动和活动参与的最佳训练方法尚不清楚，这是临床医生面临的持续挑战。：本观点概述了目前关于 CF 患者运动和身体活动与临床结局和医疗保健利用之间关系的证据，并强调了未来研究的需要。：对于 CF 患者，什么样的运动、多少运动量、多频繁、以及如何最好地支持他们进行身体活动还不确定。新的训练方法、技术的使用或药物的发展是否可以在不增加治疗负担的情况下，提供最佳的活动量和生理效益也还不清楚。目前，如果 CF 患者要进行身体活动，他们似乎应该以最有可能带来一些健康益处的方式进行这种活动，即进行至少 10 分钟的集中运动，此外还要在日常生活中进行任何偶然（习惯性）活动。
