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骨髓移植后出现Q热。

Q fever following bone marrow transplantation.

作者信息

Kanfer E, Farrag N, Price C, MacDonald D, Coleman J, Barrett A J

机构信息

Department of Haematology, Charing Cross and Westminster Medical School, London, UK.

出版信息

Bone Marrow Transplant. 1988 Mar;3(2):165-6.

PMID:3048481
Abstract

We describe a patient who developed an acute febrile illness 85 days after receiving an allogeneic bone marrow transplant for acute myeloid leukaemia. Serological investigation indicated the cause to be Q fever. The patient was receiving concurrent immunosuppressive therapy for graft-versus-host disease (GVHD). Coxiella burnetii should be added to the list of organisms which may complicate bone marrow transplantation. This case also provides further evidence to support an association between immunocompromised conditions and the development of Q fever.

摘要

我们描述了一名急性髓系白血病患者,在接受异基因骨髓移植85天后出现急性发热性疾病。血清学调查表明病因是Q热。该患者因移植物抗宿主病(GVHD)同时接受免疫抑制治疗。伯氏考克斯体应被列入可能使骨髓移植复杂化的病原体名单。该病例也为免疫功能低下状态与Q热发生之间的关联提供了进一步证据。

相似文献

1
Q fever following bone marrow transplantation.骨髓移植后出现Q热。
Bone Marrow Transplant. 1988 Mar;3(2):165-6.
2
Factors influencing the haematological recovery after allogeneic bone marrow transplantation in leukaemia patients treated with methotrexate-containing GVHD prophylaxis: a single-centre experience.含甲氨蝶呤的移植物抗宿主病预防方案治疗白血病患者异基因骨髓移植后血液学恢复的影响因素:单中心经验
Anticancer Res. 1997 Jan-Feb;17(1B):589-99.
3
Severe eosinophilia as a manifestation of acute graft-versus-host disease.严重嗜酸性粒细胞增多作为急性移植物抗宿主病的一种表现。
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4
Close simulation of acute graft-versus-host disease by interleukin-2 administered after autologous bone marrow transplantation for hematologic malignancy.自体骨髓移植治疗血液系统恶性肿瘤后给予白细胞介素-2可密切模拟急性移植物抗宿主病。
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[Aggressive ulcerous stomatitis due to the herpes simplex virus in an allogeneic bone marrow transplant. A clinical case].[异基因骨髓移植中由单纯疱疹病毒引起的侵袭性溃疡性口腔炎。一例临床病例]
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6
Bone marrow infarction due to acute graft-versus-host disease in an acute lymphoblastic leukemia patient after unrelated bone marrow transplantation.一名急性淋巴细胞白血病患者在接受非亲缘骨髓移植后,因急性移植物抗宿主病导致骨髓梗死。
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Impact of cyclosporine and methylprednisolone dose used for prophylaxis and therapy of graft-versus-host disease on survival and relapse after allogeneic bone marrow transplantation.环孢素和甲泼尼龙用于预防和治疗移植物抗宿主病的剂量对异基因骨髓移植后生存和复发的影响。
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Acute disseminated encephalomyelitis (ADEM) after allogeneic bone marrow transplantation for acute myeloid leukemia.急性髓系白血病异基因骨髓移植后发生的急性播散性脑脊髓炎(ADEM)
Ann Hematol. 2003 Jan;82(1):37-40. doi: 10.1007/s00277-002-0573-1. Epub 2002 Dec 14.
9
Severe acute graft-versus-host disease occurring after syngeneic BMT for AML in a patient not given prior cyclosporin A therapy.在一名未接受过环孢素A治疗的患者中,同基因骨髓移植治疗急性髓系白血病后发生严重急性移植物抗宿主病。
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10
Prevention of graft-versus-host disease in high risk patients by depletion of CD4+ and reduction of CD8+ lymphocytes in the marrow graft.通过去除骨髓移植物中的CD4+淋巴细胞并减少CD8+淋巴细胞来预防高危患者的移植物抗宿主病。
Bone Marrow Transplant. 1999 Mar;23(5):443-50. doi: 10.1038/sj.bmt.1701493.

引用本文的文献

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Front Med (Lausanne). 2025 Aug 18;12:1626115. doi: 10.3389/fmed.2025.1626115. eCollection 2025.
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Assessing the evidence for effective biosafety risk management in research.评估研究中有效生物安全风险管理的证据。
One Health. 2025 Aug 5;21:101159. doi: 10.1016/j.onehlt.2025.101159. eCollection 2025 Dec.
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Q Fever-Related Community Infections: United States Exposure to .
Q热相关社区感染:美国的暴露情况
Pathogens. 2025 May 8;14(5):460. doi: 10.3390/pathogens14050460.
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Current Status of Q Fever and the Challenge of Outbreak Preparedness in Korea: One Health Approach to Zoonoses.韩国 Q 热的现状和暴发准备面临的挑战:动物传染病的“同一健康”方法。
J Korean Med Sci. 2023 Jun 19;38(24):e197. doi: 10.3346/jkms.2023.38.e197.
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[Epidemiology of Q fever in Spain (2018)].[西班牙Q热的流行病学(2018年)]
Rev Esp Quimioter. 2018 Oct;31(5):386-405. Epub 2018 Jul 19.
6
Seroprevalence of antibodies and chronic Q fever among post-mortal and living donors of tissues and cells from 2010 to 2015 in the Netherlands.2010 年至 2015 年荷兰组织和细胞捐献者死后和生前血清抗体和慢性 Q 热流行率。
Euro Surveill. 2018 Mar;23(9). doi: 10.2807/1560-7917.ES.2018.23.9.17-00384.
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From Q Fever to Coxiella burnetii Infection: a Paradigm Change.从Q热到伯氏考克斯氏体感染:范式转变
Clin Microbiol Rev. 2017 Jan;30(1):115-190. doi: 10.1128/CMR.00045-16.
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Screening of post-mortem tissue donors for Coxiella burnetii infection after large outbreaks of Q fever in The Netherlands.荷兰大规模 Q 热爆发后对死后组织供体进行贝氏柯克斯体感染筛查。
BMC Infect Dis. 2014 Jan 6;14:6. doi: 10.1186/1471-2334-14-6.
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Detection of phase I IgG antibodies to Coxiella burnetii with EIA as a screening test for blood donations.酶联免疫吸附试验检测 Coxiella burnetii I 期 IgG 抗体作为献血的筛查试验。
Eur J Clin Microbiol Infect Dis. 2012 Nov;31(11):3207-9. doi: 10.1007/s10096-012-1686-7. Epub 2012 Jul 10.
10
Importance of Q fever in community acquired pneumonia.Q热在社区获得性肺炎中的重要性。
Can J Infect Dis. 1996 Nov;7(6):370-3. doi: 10.1155/1996/458960.