Kanfer E, Farrag N, Price C, MacDonald D, Coleman J, Barrett A J
Department of Haematology, Charing Cross and Westminster Medical School, London, UK.
Bone Marrow Transplant. 1988 Mar;3(2):165-6.
We describe a patient who developed an acute febrile illness 85 days after receiving an allogeneic bone marrow transplant for acute myeloid leukaemia. Serological investigation indicated the cause to be Q fever. The patient was receiving concurrent immunosuppressive therapy for graft-versus-host disease (GVHD). Coxiella burnetii should be added to the list of organisms which may complicate bone marrow transplantation. This case also provides further evidence to support an association between immunocompromised conditions and the development of Q fever.
我们描述了一名急性髓系白血病患者,在接受异基因骨髓移植85天后出现急性发热性疾病。血清学调查表明病因是Q热。该患者因移植物抗宿主病(GVHD)同时接受免疫抑制治疗。伯氏考克斯体应被列入可能使骨髓移植复杂化的病原体名单。该病例也为免疫功能低下状态与Q热发生之间的关联提供了进一步证据。