Distribution and Antimicrobial Resistance of Isolated from Pigs with Diarrhea in China.

can cause enteric diseases in humans and a wide range of animals, and even outbreaks of foodborne illness. The aim of this study was to investigate the frequency and distribution of serovars, and antimicrobial resistance in isolates from pigs with diarrhea in 26 provinces in China from 2014 to 2016. A total of 104 isolates were identified and the dominant serovar was 4,[5],12:i:- (53.9%). All isolates were resistant to trimethoprim-sulfamethoxazole, and many were resistant to ampicillin (80.8%) and tetracycline (76.9%). Among 104 isolates, was the dominant plasmid-mediated quinolone resistance gene (80.8%), followed by (47.1%). The pulsed-field gel electrophoresis results suggest that the isolates from different regions were genetically diverse, and ST34 was the most prevalent. 4,[5],12:i:- isolates is the widespread presence of heavy metal tolerance genes. The fact that the same sequence types were found in different regions and the high similarity coefficient of 4,[5],12:i:- isolates from different regions indicate the clonal expansion of the isolates, and the isolates carried various antimicrobial resistance genes. The multidrug resistant can be widely detected in pigs, which will present a challenge for farm husbandry.