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过去十年间苯并噻唑衍生物的治疗进展。

Therapeutic advancement of benzothiazole derivatives in the last decennial period.

机构信息

Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India.

出版信息

Arch Pharm (Weinheim). 2019 Jan;352(1):e1800170. doi: 10.1002/ardp.201800170. Epub 2018 Nov 29.

Abstract

Benzothiazole, a fused heterocyclic moiety, has attracted synthetic and medicinal chemists for good reasons. It is a valuable scaffold that possesses diverse biological activities, such as anticancer, anti-inflammatory, antimicrobial, antiviral, antimalarial, and anticonvulsant effects. This review mainly focusses on the recent research work on the different biological activities of benzothiazole-based compounds.

摘要

苯并噻唑是一种稠合杂环部分,由于其良好的原因,吸引了合成和药物化学家的注意。它是一种具有多种生物活性的有价值的支架,具有抗癌、抗炎、抗菌、抗病毒、抗疟和抗惊厥作用。这篇综述主要集中在苯并噻唑类化合物的不同生物活性的最新研究工作。

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