Tu Lin, Hohenberger Peter, Allgayer Heike, Cao Hui
Department of Gastrointestinal Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Division of Surgical Oncology, Mannheim University Medical Center, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Visc Med. 2018 Oct;34(5):353-358. doi: 10.1159/000494347. Epub 2018 Oct 19.
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. With the considerable research and application of molecular-targeted therapy for GISTs in the last two decades, GISTs have become a model of multidisciplinary oncological treatment. Although Western clinical guidelines are available for GISTs, such as those by the European Society of Medical Oncology (ESMO), the clinical situations in China are different from those in European countries. There are distinct differences between the clinical practice, diagnostic methods, surgical approach, and availability of new targeted agents in China and those in Europe. This review summarizes the Chinese GIST consensus guidelines compared to the European ones, which may provide an optimal approach to the diagnosis and management of GIST patients.
胃肠道间质瘤（GISTs）是胃肠道最常见的间叶组织肿瘤。在过去二十年中，随着GISTs分子靶向治疗的大量研究与应用，GISTs已成为多学科肿瘤治疗的典范。尽管有针对GISTs的西方临床指南，如欧洲医学肿瘤学会（ESMO）的指南，但中国的临床情况与欧洲国家不同。中国与欧洲在临床实践、诊断方法、手术方式以及新型靶向药物的可及性方面存在明显差异。本综述总结了中国GIST共识指南与欧洲指南的比较，可为GIST患者的诊断和管理提供最佳方法。
