Acute myeloid leukemia remodels endosteal vascular niche into a leukemic niche.
作者信息
Kumar Bijender, Chen Ching Cheng
机构信息
Department of Hematologic Malignancies and Translational Science, Beckman Research Institute of City of Hope, Duarte, CA, USA.
Department of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, USA.
出版信息
Stem Cell Investig. 2018 Oct 16;5:34. doi: 10.21037/sci.2018.09.05. eCollection 2018.
Abstract
摘要
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2
Inflammation: a key regulator of hematopoietic stem cell fate in health and disease.炎症：健康与疾病中造血干细胞命运的关键调节因子。
Blood. 2017 Oct 12;130(15):1693-1698. doi: 10.1182/blood-2017-06-780882. Epub 2017 Sep 5.
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Increased Vascular Permeability in the Bone Marrow Microenvironment Contributes to Disease Progression and Drug Response in Acute Myeloid Leukemia.骨髓微环境中血管通透性增加促进急性髓系白血病的疾病进展和药物反应。
Cancer Cell. 2017 Sep 11;32(3):324-341.e6. doi: 10.1016/j.ccell.2017.08.001. Epub 2017 Sep 1.
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Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion.急性髓系白血病通过外泌体分泌将骨髓龛转变为白血病易感性的微环境。
Leukemia. 2018 Mar;32(3):575-587. doi: 10.1038/leu.2017.259. Epub 2017 Aug 17.
5
T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments.T细胞急性白血病与骨髓微环境存在动态相互作用。
Nature. 2016 Oct 27;538(7626):518-522. doi: 10.1038/nature19801. Epub 2016 Oct 17.
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Identification of a common mesenchymal stromal progenitor for the adult haematopoietic niche.鉴定成人造血龛位的共同间充质基质祖细胞。
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