MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou 510275, P. R. China.
Chem Commun (Camb). 2018 Dec 13;54(100):14108-14111. doi: 10.1039/c8cc08570f.
Iridium complexes were used as a mitochondria-targeting agent to modify the surface of a photothermogenic nanozyme Fe3O4 nanoparticles (Ir@Fe3O4 NPs). Upon NIR irradiation, Ir@Fe3O4 NPs increase the localized temperature to 42 °C which accelerates the catalysis of ˙OH production from H2O2 resulting in excellent mild photothermal therapy.
铱配合物被用作一种线粒体靶向剂来修饰光热纳米酶 Fe3O4 纳米粒子（Ir@Fe3O4 NPs）的表面。在近红外光照射下，Ir@Fe3O4 NPs 将局部温度提高到 42°C，从而加速 H2O2 中˙OH 的产生的催化作用，从而实现优异的温和光热治疗。
