Department of Psychology, Haverford College, Haverford, PA, 19041, USA.
Department of Psychology, Haverford College, Haverford, PA, 19041, USA.
Neuropharmacology. 2019 Sep 15;156:107451. doi: 10.1016/j.neuropharm.2018.11.039. Epub 2018 Nov 28.
Although many people think of aggression as a negative or undesirable emotion, it is a normal part of many species' repertoire of social behaviors. Purposeful and controlled aggression can be adaptive in that it warns other individuals of perceived breaches in social contracts with the goal of dispersing conflict before it escalates into violence. Aggression becomes maladaptive, however, when it escalates inappropriately or impulsively into violence. Despite ample data demonstrating that impulsive aggression and violence occurs in both men and women, aggression has historically been considered a uniquely masculine trait. As a result, the vast majority of studies attempting to model social aggression in animals, particularly those aimed at understanding the neural underpinnings of aggression, have been conducted in male rodents. In this review, we summarize the state of the literature on the neurobiology of social aggression in female rodents, including social context, hormonal regulation and neural sites of aggression regulation. Our goal is to put historical research in the context of new research, emphasizing studies using ecologically valid methods and modern sophisticated techniques. This article is part of the Special Issue entitled 'Current status of the neurobiology of aggression and impulsivity'.
尽管许多人认为攻击性是一种消极或不良的情绪，但它是许多物种社会行为组合中的正常部分。有目的和可控的攻击性可以是适应性的，因为它警告其他个体感知到的违反社会契约的行为，目的是在冲突升级为暴力之前将其化解。然而，当攻击性不恰当地或冲动地升级为暴力时，它就变得适应不良了。尽管有大量数据表明冲动性攻击和暴力在男性和女性中都存在，但攻击性历来被认为是男性特有的特征。因此，绝大多数试图在动物中模拟社交攻击性的研究，特别是那些旨在理解攻击性神经基础的研究，都是在雄性啮齿动物中进行的。在这篇综述中，我们总结了雌性啮齿动物社交攻击性神经生物学的文献现状，包括社会环境、激素调节和攻击性调节的神经部位。我们的目标是将历史研究置于新研究的背景下，强调使用生态有效方法和现代复杂技术的研究。本文是题为“攻击性和冲动性神经生物学的现状”的特刊的一部分。
