Department of Veterinary Medicine, University of Cambridge, Cambridge, CB3 0ES, UK.
Department of Microbiology, Immunology & Tropical Medicine, and Research Center for Neglected Diseases of Poverty, School of Medicine & Health Sciences, George Washington University, Washington DC, 20037, USA.
Trends Parasitol. 2019 Jan;35(1):13-22. doi: 10.1016/j.pt.2018.10.007. Epub 2018 Nov 29.
There is increasing attention on the complex interactions occurring between gastrointestinal parasitic helminths and the microbial flora (microbiota) inhabiting the host gut. However, little is known about the occurrence, structure, and function of microbial populations residing within parasite organs and tissues. In this article, we argue that an in-depth understanding of the interplay between parasites and their microbiomes may significantly enhance current knowledge of parasite biology and physiology, and may lead to the discovery of entirely novel, anthelmintic-independent interventions against parasites and parasitic diseases.
人们越来越关注胃肠道寄生虫和栖息在宿主肠道中的微生物菌群（微生物群落）之间发生的复杂相互作用。然而，对于存在于寄生虫器官和组织内的微生物种群的发生、结构和功能，人们知之甚少。在本文中，我们认为，深入了解寄生虫与其微生物组之间的相互作用，可能会极大地增强人们对寄生虫生物学和生理学的现有认识，并可能导致发现全新的、不依赖驱虫药的干预寄生虫和寄生虫病的方法。
