Johns Clinton L, Jahn Andrew A, Jones Hannah R, Kush Dave, Molfese Peter J, Van Dyke Julie A, Magnuson James S, Tabor Whitney, Mencl W Einar, Shankweiler Donald P, Braze David
Haskins Laboratories, 300 George St., Suite 900, New Haven, CT, 06511, U.S.A.
Department of Clinical and Social Sciences in Psychology, University of Rochester, Melora Hall, P.O. Box 270266, Rochester, NY, 14627-0266, U.S.A.
Lang Cogn Neurosci. 2018;33(10):1275-1295. doi: 10.1080/23273798.2018.1476727. Epub 2018 May 22.
This exploratory study investigated relations between individual differences in cortical grey matter structure and young adult readers' cognitive profiles. Whole-brain analyses revealed neuroanatomical correlations with word and nonword reading ability (decoding), and experience with printed matter. Decoding was positively correlated with grey matter volume (GMV) in left superior temporal sulcus, and thickness (GMT) in right superior temporal gyrus. Print exposure was negatively correlated with GMT in left inferior frontal gyrus (pars opercularis) and left fusiform gyrus (including the visual word form area). Both measures also correlated with supramarginal gyrus (SMG), but in spatially distinct subregions: decoding was positively associated with GMV in left anterior SMG, and print exposure was negatively associated with GMT in left posterior SMG. Our comprehensive approach to assessment both confirms and refines our understanding of the novel relation between the structure of pSMG and proficient reading, and unifies previous research relating cortical structure and reading skill.
这项探索性研究调查了皮质灰质结构的个体差异与年轻成年读者认知概况之间的关系。全脑分析揭示了与单词和非单词阅读能力（解码）以及印刷品阅读经验的神经解剖学相关性。解码与左侧颞上沟的灰质体积（GMV）以及右侧颞上回的厚度（GMT）呈正相关。印刷品接触量与左侧额下回（ opercularis部）和左侧梭状回（包括视觉词形区）的GMT呈负相关。这两项测量指标也都与缘上回（SMG）相关，但在空间上不同的亚区域：解码与左侧前SMG的GMV呈正相关，而印刷品接触量与左侧后SMG的GMT呈负相关。我们全面的评估方法既证实并细化了我们对顶下小叶后部（pSMG）结构与熟练阅读之间新关系的理解，也统一了先前有关皮质结构与阅读技能的研究。
