L Kruse Lacey, Cices Ahuva, Fishbein Anna B, Paller Amy S
Division of Dermatology, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital, Chicago, Illinois.
Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Pediatr Dermatol. 2019 Jan;36(1):110-114. doi: 10.1111/pde.13710. Epub 2018 Dec 2.
BACKGROUND/OBJECTIVES: Epidemiological studies have shown an increased prevalence of attention deficit hyperactivity disorder (ADHD) in children with atopic dermatitis (AD), but many of the features of ADHD may occur as a result of the poor sleep and itch distraction associated with AD.
A case-control study was performed in children aged 6-17 years with moderate/severe AD compared with age-/sex-matched healthy controls. Participants were screened for ADHD using Vanderbilt assessments.
Seventeen patients with AD and 18 controls completed the study. Two children with AD (11.7%) and one control (5.56%) met screening criteria for ADHD via parent-completed Vanderbilt assessments; AD patients were not significantly more likely to screen positive for ADHD (P = 0.47), or comorbid behavior disorders (P = 0.23). However, AD patients were more likely than controls to exhibit ADHD-associated behaviors, most significantly inattention.
Our AD cohort did not have a significantly increased prevalence of ADHD. Certain neurocognitive symptoms are increased in children with moderate-to-severe AD compared to controls.
背景/目的：流行病学研究表明，特应性皮炎（AD）患儿中注意力缺陷多动障碍（ADHD）的患病率有所上升，但ADHD的许多特征可能是由AD相关的睡眠不佳和瘙痒干扰所致。
对6至17岁的中重度AD患儿与年龄和性别匹配的健康对照进行病例对照研究。使用范德比尔特评估对参与者进行ADHD筛查。
17例AD患者和18例对照完成了研究。通过家长完成的范德比尔特评估，2例AD患儿（11.7%）和1例对照（5.56%）符合ADHD筛查标准；AD患者筛查出ADHD阳性（P = 0.47）或共病行为障碍（P = 0.23）的可能性并无显著增加。然而，AD患者比对照更有可能表现出与ADHD相关的行为，最明显的是注意力不集中。
我们的AD队列中ADHD的患病率没有显著增加。与对照相比，中重度AD患儿的某些神经认知症状有所增加。
