Mamadalieva Nilufar Z, Sharopov Farukh S, Satyal Prabodh, Azimova Shahnoz S, Wink Michael
Nat Prod Commun. 2016 Dec;11(12):1891-1893.
The chemical composition of the essential oils obtained from aerial parts of Nepeta alatavica Lipsky, N. nuda L, and N. olgae Regel (Lamiaceae), growing wild in Central Asia (Tajikistan and Uzbekistan), were analyzed by GLC and GLC-MS. The main constituents of the essential oil from N. nuda were 1,8-cineole (24.6%), 4a-α,7-β,7a-α-nepetalactone (21.0%), germacrene D (13.5%), and β-caryophyllene (12.7%), whereas those of N. alatavica were thymol (48.5%) verbenone (7.7%), and carvacrol (7.5%). In the essential oil of N. olgae the most abundant compounds were acetylcyclohexene (31.5%), 4-tridecyne (13.2%), 2-methyl cyclopentanone (6.8%) and 1,8-cineole (6.0%). The potential antioxidant activity of these essential oils was studied by using DPPH, ABTS and FRAP assays. The essential oil of N. alatavica showed the highest in vitro free radical scavenging activity, probably due to its high thymol and carvacrol content.
对生长于中亚（塔吉克斯坦和乌兹别克斯坦）的阿尔泰荆芥（Nepeta alatavica Lipsky）、裸花荆芥（N. nuda L）和奥尔加荆芥（N. olgae Regel）（唇形科）地上部分所提取的精油的化学成分进行了气相色谱（GLC）和气相色谱 - 质谱联用（GLC-MS）分析。裸花荆芥精油的主要成分是1,8 - 桉叶素（24.6%）、4a-α,7-β,7a-α-荆芥内酯（21.0%）、杜松烯D（13.5%）和β-石竹烯（12.7%），而阿尔泰荆芥精油的主要成分是百里香酚（48.5%）、马鞭草烯酮（7.7%）和香芹酚（7.5%）。奥尔加荆芥精油中含量最高的化合物是乙酰环己烯（31.5%）、4 - 十三炔（13.2%）、2 - 甲基环戊酮（6.8%）和1,8 - 桉叶素（6.0%）。采用1,1 - 二苯基 - 2 - 三硝基苯肼（DPPH）、2,2'-联氮-二(3-乙基苯并噻唑啉-6-磺酸)二铵盐（ABTS）和铁离子还原抗氧化能力（FRAP）测定法研究了这些精油的潜在抗氧化活性。阿尔泰荆芥精油表现出最高的体外自由基清除活性，这可能归因于其高含量的百里香酚和香芹酚。
