Santosham Rajan, Santosham Rajiv, Jacob Sheba Sk, Phadke Ashwin Uday, Ponduru Trilok
1 Department of Thoracic Surgery, Santosham Chest Hospital, Chennai, India.
2 Department of Pathology, Apollo Hospital, Chennai, India.
Asian Cardiovasc Thorac Ann. 2019 Feb;27(2):132-134. doi: 10.1177/0218492318817677. Epub 2018 Dec 3.
Rosai-Dorfman disease or sinus histiocytosis is a nonmalignant disease chiefly presenting as a painless cervical lymphadenopathy, although extranodal involvement is also frequent. Involvement of the tracheobronchial tree is extremely rare, and there are no clear guidelines on management. Rosai-Dorfman disease usually presents as a tracheal tumor, although it may also present with extraluminal compression. Only 12 cases have been reported in the English language literature. Histopathology is required to confirm the diagnosis. We describe what we think is India's first reported case of histologically proven tracheal Rosai-Dorfman disease in a 40-year-old otherwise healthy lady.
罗萨伊-多夫曼病或窦性组织细胞增多症是一种非恶性疾病，主要表现为无痛性颈部淋巴结病，尽管结外受累也很常见。气管支气管树受累极为罕见，且在治疗方面没有明确的指南。罗萨伊-多夫曼病通常表现为气管肿瘤，尽管也可能表现为管腔外压迫。英文文献中仅报道了12例。确诊需要组织病理学检查。我们描述了我们认为是印度首例经组织学证实的气管罗萨伊-多夫曼病病例，患者为一名40岁的健康女性。
