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基于互联网和移动设备的精神障碍后续护理及复发预防:系统评价与未来研究建议

Internet- and mobile-based aftercare and relapse prevention in mental disorders: A systematic review and recommendations for future research.

作者信息

Hennemann Severin, Farnsteiner Sylvia, Sander Lasse

机构信息

University of Mainz, Institute of Psychology, Department of Clinical Psychology, Psychotherapy and Experimental Psychopathology, Wallstraße 3, 55122 Mainz, Germany.

University of Freiburg, Institute of Psychology, Department of Rehabilitation Psychology and Psychotherapy, Engelbergerstraße 41, 79085 Freiburg, Germany.

出版信息

Internet Interv. 2018 Oct 24;14:1-17. doi: 10.1016/j.invent.2018.09.001. eCollection 2018 Dec.

Abstract

BACKGROUND

Mental disorders are characterized by a high likelihood of recurrence. Thus, aftercare and follow-up interventions aim to maintain treatment gains and to prevent relapse. Internet- and mobile-based interventions (IMIs) may represent promising instruments in tertiary prevention. This systematic review summarizes and evaluates the research on the efficacy of IMIs as aftercare or follow-up interventions for adults with mental health issues.

METHODS

A systematic database search (PsycInfo, MEDLINE, CENTRAL) was conducted and studies selected according to predefined eligibility criteria (RCTs, adult population, clinical symptoms/disorder, assessed with validated instruments, clinical-psychological intervention rationale, aftercare/follow-up intervention, web-/mobile-based, minimum follow-up measurement of three months, inclusion of a control group). Inspected outcomes were symptom severity, recurrence- and rehospitalization rates, functioning, quality of life and adherence to primary treatment. PROSPERO CRD42017055289.

RESULTS

Sixteen RCTs met the inclusion criteria, covering trials on depression ( = 5), eating disorders ( = 4) and transdiagnostic interventions ( = 7). The majority of the interventions were based on Cognitive Behavioral Therapy (CBT) principles and were web-based ( = 11). Methodological quality of included studies was suboptimal. Limitations included attrition bias and non-specification of routine care co-interventions. IMIs yielded small to medium post-treatment effects for symptom severity ( = -0.08 -  = -0.45) in comparison to control groups. Best evidence base was found for symptom severity of depression and anxiety. Study results regarding recurrence and rehospitalization were inconsistent.

DISCUSSION

There is some evidence, that IMIs are feasible instruments for maintaining treatment gains for some mental disorders. However, further high quality, large-scale trials are needed to expand research fields, improve adherence to and uptake of IMIs and facilitate implementation of effective interventions into routine care.

摘要

背景

精神障碍的特点是复发可能性高。因此,后期护理和随访干预旨在维持治疗效果并预防复发。基于互联网和移动设备的干预措施(IMIs)可能是三级预防中有前景的手段。本系统综述总结并评估了关于IMIs作为有心理健康问题的成年人后期护理或随访干预措施有效性的研究。

方法

进行了系统的数据库检索(PsycInfo、MEDLINE、CENTRAL),并根据预定义的纳入标准选择研究(随机对照试验、成年人群、临床症状/障碍、用经过验证的工具评估、临床心理干预原理、后期护理/随访干预、基于网络/移动设备、至少三个月的随访测量、纳入对照组)。检查的结果包括症状严重程度、复发率和再住院率、功能、生活质量以及对初始治疗的依从性。国际前瞻性系统评价注册库编号CRD42017055289。

结果

16项随机对照试验符合纳入标准,涵盖抑郁症(n = 5)、饮食失调(n = 4)和跨诊断干预(n = 7)的试验。大多数干预基于认知行为疗法(CBT)原则,且为基于网络的(n = 11)。纳入研究的方法学质量欠佳。局限性包括失访偏倚和未明确常规护理联合干预措施。与对照组相比,IMIs在治疗后对症状严重程度产生了小到中等的效果(g = -0.08 - g = -0.45)。关于抑郁症和焦虑症症状严重程度的证据基础最佳。关于复发和再住院的研究结果不一致。

讨论

有证据表明,IMIs是维持某些精神障碍治疗效果的可行手段。然而,需要进一步开展高质量、大规模试验,以扩大研究领域,提高对IMIs的依从性和接受度,并促进有效干预措施在常规护理中的实施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4fd0/6205252/4edb5ee635d0/gr1.jpg

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