Zhang Lifeng, Zhang Xinmei
Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2018 Feb 25;47(4):413-418. doi: 10.3785/j.issn.1008-9292.2018.08.14.
In addition to regulating calcium and phosphorus metabolism to maintain strong bones, vitamin D also has immune regulating and anti-inflammatory effects. Moreover, it is related to chronic inflammatory diseases, autoimmune diseases and cancer. Many studies indicate the roles of vitamin D in the development and progression of endometriosis including the effects on modulation of immune responses, inflammation reactions, cell proliferation and apoptosis, angiogenesis, adhesion and invasion. Vitamin D supplementation can relieve pain and improve endometrial receptivity associated with endometriosis and play a preventive and therapeutic role. This paper summarizes the roles of vitamin D in endometriosis.
除了调节钙和磷代谢以维持强健骨骼外，维生素D还具有免疫调节和抗炎作用。此外，它与慢性炎症性疾病、自身免疫性疾病和癌症有关。许多研究表明维生素D在子宫内膜异位症的发生和发展中发挥作用，包括对免疫反应调节、炎症反应、细胞增殖与凋亡、血管生成、黏附和侵袭的影响。补充维生素D可缓解与子宫内膜异位症相关的疼痛并改善子宫内膜容受性，起到预防和治疗作用。本文总结了维生素D在子宫内膜异位症中的作用。
