[系统性红斑狼疮重叠器官特异性自身免疫性疾病的研究进展]
[Research progress on systemic lupus erythematosus overlapping organ-specific autoimmune diseases].
作者信息
Wang Xingxing, Wang Panpan, Yang Xuyan
机构信息
Department of Rheumatism and Immunology, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
Department of Endocrinology, Chengdu University of TCM, Chengdu 610075, China.
出版信息
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2018 Feb 25;47(4):435-440. doi: 10.3785/j.issn.1008-9292.2018.08.17.
Abstract
Systemic lupus erythematosus (SLE) is a multiorgan-involved autoimmune disease, and it can overlap organ-specific autoimmune diseases such as autoimmune thyroid diseases, autoimmune hepatitis and inflammatory bowel disease. There may be some association between SLE and these autoimmune diseases, such as common immunological and genetic basis, but the pathogenic mechanism is still unclear. This review focuses on current knowledge regarding the prevalence and possible pathogenesis of SLE overlapping the above three autoimmune diseases.
摘要
系统性红斑狼疮（SLE）是一种累及多器官的自身免疫性疾病，它可与器官特异性自身免疫性疾病重叠，如自身免疫性甲状腺疾病、自身免疫性肝炎和炎症性肠病。SLE与这些自身免疫性疾病之间可能存在一些关联，如共同的免疫和遗传基础，但其致病机制仍不清楚。本综述重点关注关于SLE与上述三种自身免疫性疾病重叠的患病率及可能的发病机制的现有知识。
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本文引用的文献
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