Mansour H Elsayed, Arafa S Gamal, Shehata W Abdelfatah
Internal Medicine Department, Rheumatology Division, 68792 Ain Shams University Hospital , Abbassia, Cairo, Egypt.
Lupus. 2018 Jun;27(7):1198-1201. doi: 10.1177/0961203317751857. Epub 2018 Jan 10.
A 30-year-old female presented to the rheumatology outpatient clinic of the Internal Medicine Department, Ain Shams University Hospital, Cairo, Egypt, complaining of a large right leg ulcer consistent with pyoderma gangrenosum. There was history of recurrent attacks of bleeding per rectum of one-year duration. During hospitalization she noticed blurring of vision in the left eye with diffuse blackish discoloration of the feet and toes, consistent with small-vessel vasculitis. Colonoscopy with biopsy and histopathology confirmed the diagnosis of inflammatory bowel disease-ulcerative colitis (IBD-UC). Meanwhile, the patient fulfilled the SLICC classification criteria for systemic lupus erythematosus (SLE): recurrent oral ulcers, positive antinuclear antibody testing, proteinuria >0.5 gm/24-hour urine, positive test for lupus anticoagulant and consumed C3 complement component. Herein we report a rare case of coexistence of SLE and IBD-UC.
一名30岁女性前往埃及开罗艾因夏姆斯大学医院内科的风湿病门诊就诊，主诉右腿有一个与坏疽性脓皮病相符的大溃疡。有持续一年的反复直肠出血发作史。住院期间，她注意到左眼视力模糊，双脚和脚趾弥漫性变黑，与小血管血管炎相符。结肠镜检查及活检和组织病理学确诊为炎症性肠病-溃疡性结肠炎（IBD-UC）。同时，该患者符合系统性红斑狼疮（SLE）的SLICC分类标准：复发性口腔溃疡、抗核抗体检测阳性、蛋白尿>0.5克/24小时尿、狼疮抗凝物检测阳性及补体C3成分消耗。在此我们报告一例罕见的SLE与IBD-UC共存病例。
