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轻度认知障碍患者语言训练的对照性单盲随机对照试验。

A Comparative Single-Blind Randomized Controlled Trial With Language Training in People With Mild Cognitive Impairment.

机构信息

1 Greek Alzheimer Association, Thessaloniki, Greece.

2 1st Department of Neurology, Medical School, Aristotle University of Thessaloniki, Greece.

出版信息

Am J Alzheimers Dis Other Demen. 2019 May;34(3):176-187. doi: 10.1177/1533317518813554. Epub 2018 Dec 5.

DOI:10.1177/1533317518813554
PMID:30518237
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10852481/
Abstract

BACKGROUND

Although cognitive training is effective for people with mild cognitive impairment (MCI), it is not clear which format is more effective.

OBJECTIVE

To compare the effectiveness of the same language programs when carried out via computer, paper/pencil and orally in people with MCI.

METHODS

Seventy-one participants with MCI were randomly classified in 3 experimental and 2 control groups. The experimental groups attended 48 sessions of language training for 6 months. The control groups attended either unstructured sessions or they were on waiting list.

RESULTS

Mixed measures analysis of variance, at the follow-up, showed a significant cognitive abilities improvement among the experimental versus control groups. At the end of the language training, the 3 groups presented improvement in cognitive abilities and daily function, while the control groups remained at the same performance level.

CONCLUSION

All 3 cognitive language training methods were equally significantly effective.

摘要

背景

尽管认知训练对轻度认知障碍(MCI)患者有效,但哪种模式更有效尚不清楚。

目的

比较 MCI 患者使用相同语言程序进行计算机、纸笔和口头训练的效果。

方法

71 名 MCI 患者被随机分为 3 个实验组和 2 个对照组。实验组参加了 48 次为期 6 个月的语言训练课程。对照组参加的是非结构化课程或等待名单。

结果

随访时的混合测量方差分析显示,实验组与对照组相比,认知能力有显著提高。语言训练结束时,实验组在认知能力和日常功能方面均有改善,而对照组则保持在相同的表现水平。

结论

3 种认知语言训练方法均具有显著效果。

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