霍奇金病中淋巴结和脾脏的T淋巴细胞及B淋巴细胞含量
The T and B lymphocyte content of lymph nodes and spleen in Hodgkin's disease.
作者信息
Stathopoulos G, Papamichail M, Peckham M J, Davies A J, Holborow E J
出版信息
Br J Exp Pathol. 1977 Dec;58(6):712-6.
Abstract
Lymphocytes from tumour-bearing lymph nodes in 15 patients with Hodgkin's disease, and lymphocytes from 6 spleens infiltrated by Hodgkin's tissue and 6 tumour-free spleens were studied using T and B lymphocyte markers. For comparison, lymphocytes from 16 tumour-free lymph nodes were similarly assessed. It was found that the tumour-bearing nodes showed a predominance of T lymphocytes compared with the control nodes, whereas in involved splenic tissue the proportion of T lymphocytes was slightly reduced compared with uninvolved spleens.
摘要
使用T和B淋巴细胞标志物对15例霍奇金病患者荷瘤淋巴结中的淋巴细胞、6例被霍奇金组织浸润的脾脏中的淋巴细胞以及6例无肿瘤脾脏中的淋巴细胞进行了研究。作为对照，对16例无肿瘤淋巴结中的淋巴细胞进行了类似评估。结果发现，与对照淋巴结相比，荷瘤淋巴结中T淋巴细胞占优势，而在受累脾组织中，与未受累脾脏相比，T淋巴细胞比例略有降低。
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