人B淋巴细胞对植物血凝素的促有丝分裂反应。
The mitogenic response of human B lymphocytes to phytohaemagglutinin.
作者信息
Phillips B, Weisrose E
出版信息
Clin Exp Immunol. 1974 Mar;16(3):383-92.
Abstract
Further evidence is given here of a mitogenic response to phytohaemagglutinin by human B lymphocytes. Immunofluorescent staining of unfractionated lymphocytes, and thymidine uptake by column purified populations of B and T cells, indicates that the dose–time response of these two populations is comparable. PHA transformation of B lymphocytes appears to be reduced or absent in chronic lymphocytic leukaemia.
摘要
本文提供了更多关于人B淋巴细胞对植物血凝素产生促有丝分裂反应的证据。对未分离淋巴细胞进行免疫荧光染色，以及对经柱纯化的B细胞和T细胞群体进行胸腺嘧啶核苷摄取实验，结果表明这两个群体的剂量-时间反应具有可比性。在慢性淋巴细胞白血病中，B淋巴细胞的PHA转化似乎减弱或缺失。
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