CIBER of Frailty and Healthy Aging (CIBERFES), Madrid, Spain; Hospital Virgen del Valle, Complejo Hospitalario de Toledo, Toledo, Spain; GENUD Toledo Research Group, Universidad de Castilla-La Mancha, Toledo, Spain.
GENUD Toledo Research Group, Universidad de Castilla-La Mancha, Toledo, Spain.
Exp Gerontol. 2019 Jan;115:114-121. doi: 10.1016/j.exger.2018.11.022. Epub 2018 Dec 4.
The aim was to establish whether a short supervised facility-based exercise program improved frailty, physical function and performance in comparison with usual care treatment.
This was a quasi-experimental, non-randomized controlled intervention study in frail (2.75 ± 1.25 Frailty Phenotype criteria) older adults (range:77.2-95.8 years). The exercise (EX) group (n = 11) performed concurrent training (power training + high-intensity interval training, HIIT) twice weekly for 6 weeks while the control (CT) group (n = 9) followed usual care.
The exercise intervention improved frailty status in 64% of the subjects improving Frailty Phenotype by 1.6 points (95%CI 0.8-2.5, p < 0.05), and increasing SPPB score by 3.2 points (95%CI: 2.4-4.0, Cohen's d = 2.0, p < 0.05), muscle power by 47% (95%CI: 7-87%, Cohen's d = 0.5, p < 0.05), muscle strength by 34%(95%CI: 7-60, Cohen's d = 0.6, p < 0.05) and the aerobic capacity by 19% (6 minute walking test +45 m, 95%CI: 7-83, Cohen's d = 0.7, p = 0.054). The CT did not experience any significant changes in frailty status, physical function or performance.
A short concurrent exercise program of muscle power and walking-based HIIT training is a feasible and safe method to increase physical performance and improve function and frailty in elder (pre)frail patients.
旨在确定短期监督的基于设施的锻炼计划是否与常规护理治疗相比能改善虚弱、身体功能和表现。
这是一项针对虚弱（2.75±1.25 个衰弱表型标准）老年人（年龄范围：77.2-95.8 岁）的准实验、非随机对照干预研究。锻炼（EX）组（n=11）每周进行两次协同训练（力量训练+高强度间歇训练，HIIT），持续 6 周，而对照组（CT）（n=9）则遵循常规护理。
锻炼干预使 64%的受试者的虚弱状况得到改善，使衰弱表型提高了 1.6 分（95%CI：0.8-2.5，p<0.05），并使 SPPB 评分提高了 3.2 分（95%CI：2.4-4.0，Cohen's d=2.0，p<0.05），肌肉力量提高了 47%（95%CI：7-87%，Cohen's d=0.5，p<0.05），肌肉力量提高了 34%（95%CI：7-60%，Cohen's d=0.6，p<0.05），有氧能力提高了 19%（6 分钟步行测试增加了 45 米，95%CI：7-83，Cohen's d=0.7，p=0.054）。CT 组在虚弱状态、身体功能或表现方面没有任何显著变化。
短时间的协同锻炼计划，包括肌肉力量和基于步行的 HIIT 训练，是一种可行且安全的方法，可以提高老年人（前）虚弱患者的身体表现，并改善功能和虚弱状态。
