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产桔霉素和赭曲霉毒素的丝状真菌BFE808基因组的测序与分析

Sequencing and Analysis of the Genome of the Filamentous Fungus BFE808, Which Produces the Mycotoxins Citrinin and Ochratoxin.

作者信息

Schmidt-Heydt Markus, Stoll Dominic, Geisen Rolf

机构信息

Department of Safety and Quality of Fruits and Vegetables, Max Rubner-Institut, Federal Research Institut for Nutrition and Food, Karlsruhe, Germany.

出版信息

Microbiol Resour Announc. 2018 Oct 11;7(14). doi: 10.1128/MRA.00953-18. eCollection 2018 Oct.

DOI:10.1128/MRA.00953-18
PMID:30533716
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6256647/
Abstract

Penicillium verrucosum is a filamentous ascomycete that occurs worldwide. Various cereals and the products thereof are the main habitats of this fungal species, where it produces the mycotoxins ochratoxin and citrinin. Here, we report the first draft genome sequence of P. verrucosum strain BFE808, isolated from wheat kernels.

摘要

疣孢青霉是一种丝状子囊菌，广泛分布于世界各地。各种谷物及其制品是这种真菌的主要栖息地，它在那里产生霉菌毒素赭曲霉毒素和桔霉素。在此，我们报告了从小麦籽粒中分离出的疣孢青霉菌株BFE808的首个基因组草图序列。

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1
Sequencing and Analysis of the Genome of the Filamentous Fungus BFE808, Which Produces the Mycotoxins Citrinin and Ochratoxin.产桔霉素和赭曲霉毒素的丝状真菌BFE808基因组的测序与分析
Microbiol Resour Announc. 2018 Oct 11;7(14). doi: 10.1128/MRA.00953-18. eCollection 2018 Oct.
2
Oxidative stress induces the biosynthesis of citrinin by Penicillium verrucosum at the expense of ochratoxin.氧化应激以赭曲霉毒素为代价诱导疣孢青霉合成桔霉素。
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3
Ochratoxin A producing Penicillium verrucosum isolates from cereals reveal large AFLP fingerprinting variability.从谷物中分离出的产赭曲霉毒素A的疣孢青霉菌株显示出较大的扩增片段长度多态性（AFLP）指纹图谱变异性。
J Appl Microbiol. 2005;98(3):684-92. doi: 10.1111/j.1365-2672.2004.02509.x.
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本文引用的文献

1
Description of an orthologous cluster of ochratoxin A biosynthetic genes in Aspergillus and Penicillium species. A comparative analysis.描述曲霉属和青霉属中一个赭曲霉毒素 A 生物合成基因的直系同源簇。比较分析。
Int J Food Microbiol. 2018 Mar 2;268:35-43. doi: 10.1016/j.ijfoodmicro.2017.12.028. Epub 2018 Jan 3.
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New sections in Penicillium containing novel species producing patulin, pyripyropens or other bioactive compounds.青霉属中的新分类群，包含产生展青霉素、吡唑醚菌酯或其他生物活性化合物的新物种。
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Ochratoxin A production by Penicillium thymicola.胸腺青霉产生赭曲霉毒素A。
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Oxidative stress induces the biosynthesis of citrinin by Penicillium verrucosum at the expense of ochratoxin.氧化应激以赭曲霉毒素为代价诱导疣孢青霉合成桔霉素。
Int J Food Microbiol. 2015 Jan 2;192:1-6. doi: 10.1016/j.ijfoodmicro.2014.09.008. Epub 2014 Sep 18.
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Ochratoxin A producing species in the genus Penicillium.产赭曲霉毒素 A 的青霉属种。
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Isolation and characterization of the citrinin biosynthetic gene cluster from Monascus aurantiacus.从桔青霉中分离和鉴定桔霉素生物合成基因簇。
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antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences.antiSMASH：快速识别、注释和分析细菌和真菌基因组序列中次生代谢产物生物合成基因簇。
Nucleic Acids Res. 2011 Jul;39(Web Server issue):W339-46. doi: 10.1093/nar/gkr466. Epub 2011 Jun 14.
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High-throughput functional annotation and data mining with the Blast2GO suite.使用Blast2GO套件进行高通量功能注释和数据挖掘。
Nucleic Acids Res. 2008 Jun;36(10):3420-35. doi: 10.1093/nar/gkn176. Epub 2008 Apr 29.
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Penicillium viridicatum, Penicillium verrucosum, and production of ochratoxin A.疣孢青霉、疣状青霉与赭曲霉毒素A的产生
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