胚胎小鼠胸腺细胞发育。生理水平皮质酮的增强作用。

Immunology. 1977 Aug;33(2):241-6.

The action of corticosterone on embryonic mouse thymus development has been studied in vitro. Effects of the hormone on lymphoid differentiation varied according to the dose. 0.2-1.0 microgram/ml had an enhancing effect, resulting in an increase in the proportion of Thy-1.2 positive cells as compared with control cultures. Two to fifty micrograms per millilitre had an inhibitory effect, appearing to selectively kill small lymphocytes while leaving large and medium lymphocytes intact. At higher does these immature cells were also killed.

已在体外研究了皮质酮对胚胎小鼠胸腺发育的作用。该激素对淋巴细胞分化的影响因剂量而异。0.2 - 1.0微克/毫升具有增强作用，与对照培养物相比，导致Thy - 1.2阳性细胞比例增加。每毫升2至50微克具有抑制作用，似乎能选择性杀死小淋巴细胞，而大淋巴细胞和中淋巴细胞保持完整。在更高剂量下，这些未成熟细胞也会被杀死。