培养的小鼠脾细胞中自发产生的自身反应性。II. 培养的雄性和雌性脾细胞细胞毒性的比较。
Autoreactivity developing spontaneously in cultured mouse spleen cells. II. Comparison of cytotoxicity of cultured male and female spleen cells.
作者信息
Gorczynski R M
出版信息
Immunology. 1976 Oct;31(4):615-23.
Abstract
Male and female spleen cells were compared before and after culture for their cytotoxicity to autologous-embryo fibroblasts. Cultures of male cells developed significantly greater reactivity than cultures of female cells. Moreover, while the cytotoxicity derived from cultures of male cells was totally abolished by treatment of effector cells with a mouse anti-T cell antiserum, such an antiserum had less affect on the effector cells of female mouse cultures.
摘要
对雄性和雌性脾细胞在培养前后针对自体胚胎成纤维细胞的细胞毒性进行了比较。雄性细胞培养物产生的反应性明显高于雌性细胞培养物。此外，用小鼠抗T细胞抗血清处理效应细胞后，雄性细胞培养物产生的细胞毒性完全消除，而这种抗血清对雌性小鼠培养物的效应细胞影响较小。
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本文引用的文献
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Studies of allograft immunity in mice. I. Induction, development and in vitro assay of cellular immunity.小鼠同种异体移植免疫研究。I. 细胞免疫的诱导、发展及体外检测
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Cell-mediated immune response in vitro. 3. The requirement for macrophages in cytotoxic reactions against cell-bound and subcellular alloantigens.体外细胞介导的免疫反应。3. 针对细胞结合型和亚细胞同种异体抗原的细胞毒性反应中巨噬细胞的需求。
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Effect of anti-embryo immunization on methylcholanthrene-induced sarcoma growth in BALB/c mice.抗胚胎免疫对甲基胆蒽诱导的BALB/c小鼠肉瘤生长的影响。
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