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开发损伤风险模型以指导机动车碰撞后急诊科的CT评估。

Development of injury risk models to guide CT evaluation in the emergency department after motor vehicle collisions.

作者信息

Hartka Thomas, Glass George, Kao Christopher, McMurry Timothy

机构信息

a Department of Emergency Medicine , University of Virginia , Charlottesville , Virigina.

b School of Medicine , University of Virginia , Charlottesville , Virigina.

出版信息

Traffic Inj Prev. 2018;19(sup2):S114-S120. doi: 10.1080/15389588.2018.1543872. Epub 2018 Dec 13.

Abstract

OBJECTIVE

The clinical evaluation of motor vehicle collision (MVC) victims is challenging and commonly relies on computed tomography (CT) to detect internal injuries. CT scans are financially expensive and each scan exposes the patient to additional ionizing radiation with an associated, albeit low, risk of cancer. Injury risk prediction based on regression modeling has been to be shown to be successful in estimating Injury Severity Scores (ISSs). The objective of this study was to (1) create risk models for internal injuries of occupants involved in MVCs based on CT body regions (head, neck, chest, abdomen/pelvis, cervical spine, thoracic spine, and lumbar spine) and (2) evaluate the performance of these risk prediction models to predict internal injury.

METHODS

All Abbreviated Injury Scale (AIS) 2008 injury codes were classified based on which CT body region would be necessary to scan in order to make the diagnosis. Cases were identified from the NASS-CDS. The NASS-CDS data set was queried for cases of adult occupants who sought medical care and for which key crash characteristics were all present. Forward stepwise logistic regression was performed on data from 2010-2014 to create models predicting risk of internal injury for each CT body region. Injury risk for each region was grouped into 5 levels: very low (<2%), low (2-5%), medium (5-10%), high (10-20%), and very high (20%). The models were then tested using weighted data from 2015 in order to determine whether injury rates fell within the predicted risk level.

RESULTS

The inclusion and exclusion criteria identified 5,477 cases in the NASS-CDS database. Cases from 2010-2014 were used for risk modeling (n = 4,826). Seven internal injury risk models were created based on the CT body regions using data from 2010-2014. These models were tested against data from 2015 (n = 651). In all CT body regions, the majority of occupants fell in the very low or low predicted injury rate groups, except for the head. On average, 57% of patients were classified as very low risk and 15% as low risk for each body region. In most cases the actual rate of injury was within the predicted injury risk range. The 95% confidence interval overlapped with predicting injury risk range in all cases.

CONCLUSION

This study successfully demonstrated the ability for internal injury risk models to accurately identify occupants at low risk for internal injury in individual body regions. This represents a step towards incorporating telemetry data into a clinical tool to guide physicians in the use of CT for the evaluation of MVC victims.

摘要

目的

机动车碰撞(MVC)受害者的临床评估具有挑战性,通常依靠计算机断层扫描(CT)来检测内伤。CT扫描成本高昂,且每次扫描都会使患者暴露于额外的电离辐射中,尽管致癌风险较低,但仍存在相关风险。基于回归模型的损伤风险预测已被证明在估计损伤严重程度评分(ISS)方面是成功的。本研究的目的是:(1)基于CT身体区域(头部、颈部、胸部、腹部/骨盆、颈椎、胸椎和腰椎)为MVC事故中的驾乘人员创建内伤风险模型;(2)评估这些风险预测模型预测内伤的性能。

方法

根据为做出诊断所需扫描的CT身体区域,对所有2008年简略损伤量表(AIS)损伤代码进行分类。从国家汽车抽样系统 - 碰撞数据系统(NASS - CDS)中识别病例。查询NASS - CDS数据集,查找寻求医疗护理且关键碰撞特征齐全的成年驾乘人员病例。对2010 - 2014年的数据进行向前逐步逻辑回归,以创建预测每个CT身体区域内伤风险的模型。每个区域的损伤风险分为5个级别:极低(<2%)、低(2 - 5%)、中(5 - 10%)、高(10 - 20%)和极高(20%)。然后使用2015年的加权数据对模型进行测试,以确定损伤率是否落在预测风险水平内。

结果

纳入和排除标准在NASS - CDS数据库中识别出5477例病例。2010 - 2014年的病例用于风险建模(n = 4826)。基于CT身体区域,利用2010 - 2014年的数据创建了7个内伤风险模型。这些模型针对2015年的数据(n = 651)进行了测试。在所有CT身体区域中,除头部外,大多数驾乘人员属于预测损伤率极低或低的组。平均而言,每个身体区域57%的患者被分类为极低风险,15%为低风险。在大多数情况下,实际损伤率在预测损伤风险范围内。所有情况下,95%置信区间与预测损伤风险范围重叠。

结论

本研究成功证明了内伤风险模型能够准确识别个体身体区域内伤低风险的驾乘人员。这代表着朝着将遥测数据纳入临床工具迈出了一步,以指导医生在评估MVC受害者时使用CT。

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