Malpica Anais, Euscher Elizabeth D, Hecht Jonathan L, Ali-Fehmi Rouba, Quick Charles M, Singh Naveena, Horn Lars-Christian, Alvarado-Cabrero Isabel, Matias-Guiu Xavier, Hirschowitz Lynn, Duggan Máire, Ordi Jaume, Parkash Vinita, Mikami Yoshiki, Ruhul Quddus M, Zaino Richard, Staebler Annette, Zaloudek Charles, McCluggage W Glenn, Oliva Esther
Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas (A.M., E.D.E.) Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School (J.L.H.) Department of Pathology, Massachusetts General Hospital and Harvard Medical School (E.O.), Boston, Massachusetts Department of Pathology, Wayne State University, Detroit, Michigan (R.A.F.) Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas (C.M.Q.) Department of Cellular Pathology, Barts Health NHS Trust, London (N.S.) Department of Cellular Pathology, Birmingham Women's NHS Trust, Birmingham (L.H.), UK Division of Gynecologic, Breast and Perinatal Pathology, University Hospital, Leipzig (L.C.H.) Institute of Pathology, University Hospital of Tübingen, Tübingen (A.S.), Germany Department of Pathology, Hospital de Oncología Siglo XXI, Mexico City, Mexico City, Mexico (I.A.C.) Department of Pathology, Hospital Universitari de Bellvitge and Hospital Universitari de Arnau de Vilanova, Idibell, Irblleida, and Universitat de Lleida, Ciberonc (X.M.G.) Department of Pathology, Hospital Clinic of Barcelona, Universitat de Barcelona, Barcelona (J.O.), Spain Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Alberta, Canada (M.D.) Department of Pathology, Yale University School of Medicine, New Haven, Connecticut (V.P.) Department of Diagnostic Pathology, Kumamoto University Hospital, Kumamoto, Japan (Y.M.) Department of Pathology, Women and Infants Hospital and The Warren Alpert Medical School of Brown University, Providence, Rhode Island (M.R.Q.) Division of Anatomic Pathology, Hershey Medical Center, Pennsylvania State University, Hershey, Pennsylvania (R.Z.) Department of Pathology, University of California, San Francisco, San Francisco, California (C.Z.) Department of Pathology, Belfast Health and Social Care Trust, Belfast, UK (W.G.M.).
Int J Gynecol Pathol. 2019 Jan;38 Suppl 1(Iss 1 Suppl 1):S9-S24. doi: 10.1097/PGP.0000000000000552.
Endometrial cancer is the most common gynecologic neoplasm in developed countries; however, updated universal guidelines are currently not available to handle specimens obtained during the surgical treatment of patients affected by this disease. This article presents recommendations on how to gross and submit sections for microscopic examination of hysterectomy specimens and other tissues removed during the surgical management of endometrial cancer such as salpingo-oophorectomy, omentectomy, and lymph node dissection-including sentinel lymph nodes. In addition, the intraoperative assessment of some of these specimens is addressed. These recommendations are based on a review of the literature, grossing manuals from various institutions, and a collaborative effort by a subgroup of the Endometrial Cancer Task Force of the International Society of Gynecological Pathologists. The aim of these recommendations is to standardize the processing of endometrial cancer specimens which is vital for adequate pathological reporting and will ultimately improve our understanding of this disease.
子宫内膜癌是发达国家最常见的妇科肿瘤；然而，目前尚无最新的通用指南来处理该疾病患者手术治疗期间获取的标本。本文就如何大体检查和提交子宫切除术标本以及子宫内膜癌手术管理过程中切除的其他组织（如输卵管卵巢切除术、网膜切除术和淋巴结清扫术——包括前哨淋巴结）的切片进行显微镜检查提出建议。此外，还讨论了其中一些标本的术中评估。这些建议基于文献综述、各机构的大体检查手册以及国际妇科病理学家协会子宫内膜癌特别工作组一个小组的合作努力。这些建议的目的是规范子宫内膜癌标本的处理，这对于充分的病理报告至关重要，并最终将增进我们对这种疾病的了解。
