Botha Willem J, Schoeman Johan P, Marks Stanley L, Whitehead Zandri, Annandale Cornelius H
Department of Companion Animal Clinical Studies, University of Pretoria.
J S Afr Vet Assoc. 2018 Dec 5;89(0):e1-e6. doi: 10.4102/jsava.v89i0.1731.
Salmonellosis is a disease of major zoonotic importance and canine parvovirus is a potentially fatal cause of canine enteritis with a world-wide distribution. Persistent isolation of Salmonella during routine environmental sampling surveys of a hospital ward, reserved for the treatment of dogs with canine parvovirus infection, prompted investigation into a possible source. We hypothesised that dogs affected by canine parvovirus would have a higher prevalence of faecal salmonellae compared to an apparently healthy cohort. Seventy-four client-owned dogs naturally infected with canine parvovirus and 42 apparently healthy client-owned dogs were included in the study. This prospective, longitudinal, observational study was conducted over an 18-month period. Fresh faecal samples were collected from dogs aged 6 weeks to 9 months diagnosed with canine parvovirus infection and admitted for treatment, and from apparently healthy dogs presented for vaccination or routine hospital procedures. Faeces were submitted for the isolation, antimicrobial susceptibility testing and serotyping of salmonellae. The prevalence of faecal Salmonella shedding was 22% and 31% for the affected and apparently healthy dogs, respectively, which was not statistically different. No significant associations between Salmonella status and possible risk factors or continuous variables such as age, body weight and duration of hospitalisation were identified. All the Salmonella isolates (n = 32) were resistant to penicillin G, lincomycin and tylosin. Salmonellae from nine different serotypes were identified. The prevalence of Salmonella shedding in both groups was higher than that commonly reported, yet similar to those in previous reports on young dogs, shelter dogs or dogs fed a raw meat diet.
沙门氏菌病是一种具有重要人畜共患病意义的疾病，犬细小病毒是犬肠炎的一个潜在致命病因，在全球范围内均有分布。在一个专门用于治疗感染犬细小病毒的犬只的医院病房进行的常规环境采样调查中，持续分离出沙门氏菌，这促使人们对可能的来源展开调查。我们假设，与表面健康的犬只群体相比，感染犬细小病毒的犬只粪便中沙门氏菌的携带率会更高。本研究纳入了74只自然感染犬细小病毒的客户拥有犬和42只表面健康的客户拥有犬。这项前瞻性、纵向观察性研究持续了18个月。从年龄在6周龄至9月龄、被诊断为感染犬细小病毒并入院治疗的犬只，以及前来接种疫苗或进行常规医院检查的表面健康犬只采集新鲜粪便样本。将粪便送检以进行沙门氏菌的分离、抗菌药敏试验和血清分型。受影响犬只和表面健康犬只粪便中沙门氏菌的携带率分别为22%和31%，两者无统计学差异。未发现沙门氏菌携带状况与可能的风险因素或年龄、体重、住院时间等连续变量之间存在显著关联。所有沙门氏菌分离株（n = 32）均对青霉素G、林可霉素和泰乐菌素耐药。鉴定出了9种不同血清型的沙门氏菌。两组中沙门氏菌的携带率均高于通常报道的水平，但与之前关于幼犬、收容所犬或喂食生肉饮食的犬只的报道相似。
